We present a case of subperiosteal giant-cell reparative granuloma followed over six years showing the complete evolution from the early phase of subperiosteal haematoma to the end stage of an ossified haematoma. Such lesions, although they are histologically similar to true giant-cell tumours, can be distinguished by the patients' age, their location on the diaphysis, and by their radiological...

The aetiopathogenesis of epuli, a group of benign gingival hyperplasias, remains unclear. The purpose of the present study was to determine similarities and differences between benign (epulus) and malignant (cancer) gingival hyperplasias based on the evaluation of three signal pathways stimulated by the IFN-gamma complex. Five gingival specimens sampled from giant cell epulus, fibrous epulus, c...

Introduction: Granuloma pyogenicum or pyogenic granuloma is common benign vascular lesion of oral cavity mucous membrane and skin particularly in children and young adult fingers. Most of granuloma pyogenicum achieve a size of about 2 cm but giant variant can achieve a size of more than 4–5 cm. Giant granuloma pyogenicum of scalp is a occasionally reported. Giant and multiple granuloma pyogenic...

Introduction: Despite similar histopathological features, peripheral giant cell granuloma (PGCG) and central giant cell granuloma (CGCG) differ in their biological behavior. PGCG and CGCG are hemorrhagic/vascular lesions, clinically and microscopically. Angiogenesis is necessary for the growth and development of lesions and affects their clinical behavior. CD105 is a useful vascular marker for...

It has been emphasized by Sheehan (1948) that the criterion for the diagnosis of hypopituitarism is destruction of the anterior pituitary, the most frequent cause being post-partum necrosis. Hypopituitarism in the male is relatively uncommon. Escamilla and Lisser (1942), in a survey of 101 " typical clinical cases with pathological verification," found only 35 in the male. The following case, w...