Parallel hyper-cubic gene expression programming (GEP) was constructed to estimate the slump flow of high-performance concrete (HPC) by using seven concrete ingredients. HPC is a highly complex material; because modeling its behavior is extremely difficult, robust optimization techniques are required. Because of complications caused by high dimensionality, obtaining globally optimal or nearly o...

Neuroendocrine tumours of the gastroenteropancreatic tract (GEP-NETs) comprise a group of very heterogeneous neoplasms, which are considered 'rare diseases'. Epidemiological studies on the incidence of GEP-NETs worldwide have reported a remarkable increase in the detection of these tumours. In a recent study, based on pathology reports (PALGA) to investigate the incidence of pancreatic and duod...

We previously reported that transcription factor XBP1S binds to RUNX2 and enhances chondrocyte hypertrophy through acting as a cofactor of RUNX2. Herein, we report that XBP1S is a key downstream molecule of BMP2 and is required for BMP2-mediated chondrocyte differentiation. XBP1S is up-regulated during chondrocyte differentiation and demonstrates the temporal and spatial expression pattern duri...

Gene Expression Programming (GEP) aims at discovering essential rules hidden in observed data and expressing them mathematically. GEP has been proved to be a powerful tool for constructing efficient classifiers. Traditional GEP-classifiers ignore the distribution of samples, and hence decrease the efficiency and accuracy. The contributions of this paper include: (1) proposing two strategies of ...

Although previously considered rare, recent epidemiological studies have revealed that the incidence (3.6/100,000) and prevalence (35/100,000) of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) has increased over the past few decades. Despite the progress in the understanding of GEP-NET molecular biology, there is still little advance in the early diagnosis due to lack of specific tumor...

In diagnosis of lung cancer, rapid distinction between small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) tumors is very important. Serum markers, including lactate dehydrogenase (LDH), C-reactive protein (CRP), carcino-embryonic antigen (CEA), neurone specific enolase (NSE) and Cyfra21-1, are reported to reflect lung cancer characteristics. In this study classification of lun...

Although colon cancer is the third most common cause of cancer-related death worldwide, the prevalence of gastroenteropancreatic neuroendocrine tumours (GEP-NETs) remains rare. To date, very few cases of GEP-NETs within Meckel's diverticulum and synchronous colorectal cancer have been reported. Although the coexistence of these two tumour types is uncommon, it is important to be aware of their ...

Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are a rare and heterogeneous group of tumors arising from the cells of diffuse endocrine system (DES) scattered through the mucosa of the gastrointestinal tract and pancreas. Tumors were historically termed carcinoid-«cancer-like» due to better prognosis than adenocarcinoma. Yearly incidence of GEP-NETs is estimated to be 1-2 of 100.000 po...

The Generation expansion planning (GEP) problem is a large scale, mixed integer and the most complicated optimization problem. So we are using Multi-objective differential evolution (MODE) for solving the GEP problem. To calculate for best combinations of conventional sources with and without wind farm, GEP problem is considered for test system of and satisfy the constraints by calculating EENS...

BACKGROUND Gastro-entero-pancreatic neuroendocrine neoplasms (GEP-NEN) are relatively rare tumors, not equally distributed in the gastrointestinal system. In 2010, a revised version of the WHO classification of GEP-NENs was published. This study reports for the first time the distribution and characteristics of GEP-NENs in a Lebanese population. MATERIALS AND METHODS This descriptive retrospe...