Conformational isomerism of a ball-shaped cyclophane of cyclen was studied using NMR and computational methods with the most notable conformer containing a highly symmetric cyclic benzene tetramer.

An unprecedented example of supramolecular isomerism based on 2D hydrogen-bonded multi-component networks that leads to the preparation of different photoproducts via a topochemical transformation is reported.

Aims: Evidence is emerging that, in the setting of isomerism, atrial and bronchial arrangement are not always concordant, nor these patterns harmonious with abdominal organs. We aimed to evaluate concordance between features a cohort patients cardiac malformations known seeking determine whether it was feasible assess complexity on this basis, regard taking note potential value as opposed appen...

BACKGROUND Atrioventricular septal defects (AVSD) are very commonly diagnosed in utero. Heterotaxy/chromosomal abnormalities frequently coexist with AVSD. However, outcomes of fetal AVSD are not precisely known. We attempted to define mortality risk factors in AVSD. METHOD We retrospectively searched our database, electronic records, and echocardiograms with diagnosis of fetal AVSD from 2003 ...

OBJECTIVE The purpose of this study was to evaluate the accuracy of the prenatal diagnosis of left isomerism and to assess possible diagnostic and prognostic markers. METHODS We conducted a retrospective review of all previously unpublished cases of left isomerism diagnosed in the prenatal and postnatal periods in 2 tertiary referral centers in Germany over 15 years. RESULTS Among 34 fetuse...

OBJECTIVES To clarify the prevalence and mechanism of supraventricular tachycardia in patients with right atrial isomerism. BACKGROUND Paired SA and dual atrioventricular (AV) nodes have been described in patients with right atrial isomerism. However, the clinical significance remains unclear. METHODS From 1987 to 1996, a total of 101 patients (61 male, 40 female) and four fetuses were iden...

BACKGROUND Supraventricular tachycardia (SVT) is common in complex congenital heart disease (CCHD) patients with single-ventricle physiology and may cause hemodynamic deterioration. We reported the outcomes of catheter ablation for such complex SVT in these single-ventricle CCHD patients. METHODS AND RESULTS Patients with single-ventricle physiology (defined as CCHD patients) who received ele...