We use >250,000 cross-over events identified in >10,000 bovine sperm cells to perform an extensive characterization of meiotic recombination in male cattle. We map Quantitative Trait Loci (QTL) influencing genome-wide recombination rate, genome-wide hotspot usage, and locus-specific recombination rate. We fine-map three QTL and present strong evidence that genetic variants in REC8 and RNF212 in...

the main objective for plant breeding is to increase genetic diversity. mutation induction is a method to increase genetic diversity associated with selection, recombination, or a combination of these approaches in plant breeding. the present research was aimed to compare efficacy of different doses of gamma rays (150, 200, 250, 300 and 350 gy and zero dose control) on the sesame morphological ...

Plants do it. Animals do it. People do it, too. During meiosis—the cell division that creates eggs and sperm—all these organisms mix the genetic material inherited from their mother and father. This mixing is called recombination, and it results from crossover events, where pairs of chromosomes swap genetic material. Evolutionary biologists have long known that recombination seems to increase g...

T H E frequency of genetic recombination in phage crosses is often taken as a measure of the physical separation between the mutated nucleotide sites; the smaller the recombination frequency, the smaller the separation. Assuming the nucleotide is an indivisible molecular unit of heredity, a lower limit to the recombination frequencies between point mutants might be expected, corresponding to mu...

A current high priority research goal is to understand how genetic variations influence complex genetic diseases (or more generally traits). Recombination is an important biological and genetic process that plays a major role in the logic behind association mapping, a currently intensely studied method widely hoped to efficiently find genes (alleles) associated with complex diseases. Recently, ...

Recombination is a ubiquitous genetic process which results in the exchange of DNA between two substrates. Homologous recombination occurs between DNA species with identical sequence whereas illegitimate recombination can occur between DNA with very little or no homology. Site-specific recombination is often used by temperate phages to stably integrate into bacterial chromosomes. Characterisati...