نتایج جستجو برای: genetic linkage analysis

تعداد نتایج: 3297133  

Daryush Talei Masoomeh Rajabi Hashjin Mohammad Hossein Fotokian Mohsen Mohammadi Mostafa Agahee Sarbrzeh

Genetic  diversity  is  the  basis  of  the  natural  evolution  of  plant  breeding  and  biological  system  are  important  components  of  sustainability. The aim of this study was to evaluate 116 genotypes of Triticum turgidum from seven countries in terms of morphological traits. The results showed that high significant differences among the genotypes. The correlation between gra...

Journal: :international journal of molecular and cellular medicine 0
somayeh reiisi medical genetics department, national institute of genetic engineering and biotechnology (nigeb).سازمان اصلی تایید شده: پژوهشگاه ملی مهندسی ژنتیک و زیست فناوری mohammad hosein sanati medical genetics department, national institute of genetic engineering and biotechnology (nigeb).سازمان اصلی تایید شده: پژوهشگاه ملی مهندسی ژنتیک و زیست فناوری mohammad amin tabatabaiefar medical genetics department, ahvaz jundishapur university of medical sciences, ahvaz, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی جندی شاپور اهواز (ahvaz jundishapur university of medical sciences) shahla ahmadian cellular and molecular research center, shahrekord university of medical sciences, shahrekord, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهرکرد (shahr kord university of medical sciences) salimeh reiisi biochemistry department, maleke-ashtar university of technology, tehran iran. shahrbanoo parchami cellular and molecular research center, shahrekord university of medical sciences, shahrekord, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهرکرد (shahr kord university of medical sciences)

sensorineural non-syndromic hearing loss is the most common disorder which affects 1 in 500 newborns. hearing loss is an extremely heterogeneous defect with more than 100 loci identified to date. according to the studies, mutations in gjb2 are estimated to be involved in 50- 80% of autosomal recessive non-syndromic hearing loss cases, but contribution of other loci in this disorder is yet ambig...

Journal: :Statistical applications in genetics and molecular biology 2011
Omer Weissbrod Dan Geiger

Germline mosaicism is a genetic condition in which some germ cells of an individual contain a mutation. This condition violates the assumptions underlying classic genetic analysis and may lead to failure of such analysis. In this work we extend the statistical model used for genetic linkage analysis in order to incorporate germline mosaicism. We develop a likelihood ratio test for detecting whe...

2012
Dirk Thierens Peter A. N. Bosman

We define the linkage model evolvability and the evolvabilitybased fitness distance correlation. These measures give an insight in the search characteristics of linkage model building genetic algorithms. We apply them on the linkage tree genetic algorithm for deceptive trap functions and the nearest-neighbor NK-landscape problem. Comparisons are made between linkage trees, based on mutual infor...

2016
Xiangqing Sun Robert Elston Gary W. Falk William M. Grady Ashley Faulx Sumeet K. Mittal Marcia I. Canto Nicholas J. Shaheen Jean S. Wang Prasad G. Iyer Julian A. Abrams Joseph E. Willis Kishore Guda Sanford Markowitz Jill S. Barnholtz‐Sloan Apoorva Chandar Wendy Brock Amitabh Chak

BACKGROUND Familial aggregation and segregation analysis studies have provided evidence of a genetic basis for esophageal adenocarcinoma (EAC) and its premalignant precursor, Barrett's esophagus (BE). We aim to demonstrate the utility of linkage analysis to identify the genomic regions that might contain the genetic variants that predispose individuals to this complex trait (BE and EAC). METH...

2010
Cecilia McGregor Jason Michael Prothro David Knauft Ron Walcott

UNDERLYING HORTICULTURALLY IMPORTANT TRAITS IN WATERMELON by JASON MICHAEL PROTHRO (Under the Direction of Cecilia McGregor) ABSTRACT QTL analysis was performed for multiple traits in an elite x egusi and an elite x citron F2 population of watermelon (Citrullus lanatus var. lanatus Thunb.). Two linkage maps were constructed for QTL analysis using single nucleotide polymorphism (SNP) markers. A ...

Journal: :Genetic epidemiology 2001
S Zhang K Zhang J Li F Sun H Zhao

Many statistical methods have been proposed in recent years to test for genetic linkage and association between genetic markers and traits of interest through unrelated nuclear families. However, most of these methods are not valid tests of association in the presence of linkage when some of the nuclear families are related. As a result, related nuclear families in large pedigrees cannot be inc...

Journal: :Genome 2005
M Pekkinen S Varvio K K M Kulju H Kärkkäinen S Smolander A Viherä-Aarnio V Koski M J Sillanpää

The first genetic linkage map for silver birch, Betula pendula Roth, was constructed by using a pseudo-testcross mapping strategy and integration of linkage data from 3 unrelated 2-generation pedigrees. The map is based on the genetic inheritance and segregation of 82 amplified fragment length polyhmorphisms and 19 microsatellite markers, and was constructed by simultaneously comparing the perf...

Journal: :international journal of advanced biological and biomedical research 2014
masoomeh rajabi hashjin mohammad hossein fotokian mostafa agahee sarbrzeh mohsen mohammadi daryush talei

genetic  diversity  is  the  basis  of  the  natural  evolution  of  plant  breeding  and  biological  system  are  important  components  of  sustainability. the aim of this study was to evaluate 116 genotypes of triticum turgidum from seven countries in terms of morphological traits. the results showed that high significant differences among the genotypes. the correlation between grain yield ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - پژوهشگاه ملی مهندسی ژنتیک وزیست فناوری - دانشکده پزشکی 1389

گلوکوم بیماری پیچیده چشم معمولا" همراه با افزایش فشار داخل چشم و آسیب عصب بینایی و فنجانی شدن سر عصب بینایی است ، بطوریکه می تواند در اثر عدم یا تاخیر درمان مو جب از دست رفتن بینایی گردد. گلوکوم بر اساس اتیولوژی (اولیه یا ثانویه) ،آ ناتومی اتاقک قدامی (زاویه باز یا بسته) و زمان بروز علایم (کودکی و بزرگسالی) به سه دسته گلوکوم زاویه باز اولیه، گلوکوم زاویه بسته اولیه و گلوکوم مادرزادی اولیه تقسیم...

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