Background: Graves’ disease (GD), a highly rampant autoimmune disorder of the thyroid gland, is responsible for 60-80% of the clinical cases of hyperthyroidism. Over the past decades, genetic association studies have identified several GD susceptibility loci in CTLA-4, TSHR and major histocompatibility complex regions. The information on the association between the human leukocyte antigens (HLA...

Institute of Neuroscience and Medicine, INM-5: Nuclear Chemistry, Research Centre Jülich, Germany Application of radiolabelled, existing MRI probes using a suitable reporter group for multimodal PET(SPECT)/MRI imaging is limited due to the required alteration of the molecular structure and thus changing their in vivo properties. Radiolabelling of existing MRI contrast agents with PET(SPECT) iso...

Z. Naturforsch. 55 b, 1131-1136 (2000); received July 24, 2000 Heterodinuclear Complex, Super-Exchange Interactions, Lanthanides Preparation, crystal structure and magnetic properties of a heterodinuclear complex, LCu(Me2C0 )Gd(N03)3 (L = (N,N'-bis(3-methoxysalicylidene)propane1,2-diamine) are re­ ported. The crystal structure of the complex was determined by X-ray diffraction methods at 200 K....

Herpes simplex virus (HSV) entry requires the interaction between the envelope glycoprotein D (gD) and a cellular receptor such as nectin-1 (also named herpesvirus entry mediator C [HveC]) or HveA/HVEM. Nectin-1 is a cell adhesion molecule found at adherens junctions associated with the cytoplasmic actin-binding protein afadin. Nectin-1 can act as its own ligand in a homotypic interaction to br...

The mononuclear Gd(III) complex, [Gd(L)3(H2O)5] (where L is alizarin yellow R (NaC13H8N3O5)), has been prepared in H2O under reflux condition. The Gd(III) complex has been characterized by elemental analysis and spectroscopic methods (UV–Vis and FT–IR). The Gd2O3 nanoparticles were prepared by the calcination of the Gd(III) complex in air at different temperatures up to 600 °C for 2 h. The calc...

A plane is a two-dimensional right vector space V over a division algebra D, which we assume in this paper has an involution; a hermitian form h : V × V −→ D is hyperbolic, if, with respect to a properly choosen basis, it is given by the matrix 0 1 1 0 ) ; the pair (V, h) is called a hyperbolic plane. If D is central simple over a number field K, a hyperbolic plane (V, h) gives rise to a reduct...

Luminophores Gd 2 O S : Tb(3-7 mol.%), obtained through the stage of sol-gel formation 3 Tb precursors with their subsequent sulfidation in sulfur vapor LiF flux at 700 o C, showed high luminescence efficiency. The characterization samples by a set physicochemical methods established that an increase concentration 3+ activator leads to its specific distribution: over gadolinium vacancies (V )''...

The symbol-error rate (SER) of a quadrature subbranch hybrid selection/maximal-ratio combining scheme for 1-D modulations in Rayleigh fading under employment of the generalized detector (GD), which is constructed based on the generalized approach to signal processing in noise, is investigated. At the GD, N diversity branches are split into 2N in-phase and quadrature subbranches. Traditional hyb...

The thermodynamic stabilities of the Gd(III) complexes of five hexadentate ligands, which incorporate the 2,3-dihydroxyterephthalamide and 2,3-hydroxypyridonate chelating moieties, have been determined by potentiometric and spectrophotometric titration. The ligands were chosen to span a range of basicities while maintaining a similar tripodal structural motif, facilitating a study of the effect...