Brain stem gliomas may present as gastro-oesophageal reflux. In such cases gastro-oesophageal reflux presents atypically late, and computed tomography may not detect the presence of the tumour until late in the course of the disease.

BACKGROUND This study describes the burden of bleeding oesophageal varices at the main tertiary referral centre in Accra. DESIGN Retrospective design to describe the endoscopic spectrum and review mortality data following acute upper gastro-intestinal bleeding at the Korle-Bu Teaching Hospital. Endoscopic data was reviewed in the Endoscopy Unit between 2007 and 2010. Mortality data was collat...

Eleven adult patients with nocturnal asthma, and gastro-oesophageal reflux documented by endoscopy or ambulatory oesophageal pH monitoring completed a double-blind cross-over study (4 week treatment, one week run-in and cross-over periods) comparing the effects of omeprazole 20 mg daily and placebo on asthma control assessed by symptoms, peak expiratory flow rate and bronchodilator usage. Omepr...

Varices most commonly occur and bleed in the gastro-esophageal region but ectopic varices can arise at extra-gastro-esophageal locations in the gastrointestinal tract like duodenum, jejunum, ileum, colon, rectum, biliary tree and at the site of a surgical ostomy. These varices pose diagnostic as well as therapeutic challenges during endoscopic procedures. Ectopic varices can also occur outside ...

The association between gastro-oesophageal reflux and sleep state in 24 infants with confirmed or suspected gastro-oesophageal reflux was studied by monitoring both the pH in the lower oesophagus and polygraphic tracings made during sleep at night. Gastro-oesophageal reflux during the night was confirmed in 20 infants. Three hundred and sixteen precipitous drops of more than one unit of pH were...

Oral controlled release and site specific drug delivery system has been of great interest in pharmaceutical field to achieve improved therapeutic advantage. Drug absorption in the gastrointestinal tract is a highly variable procedure and prolonging gastric retention of the dosage form extends the time for drug absorption. Gastro retentive drug delivery system is one of such novel approaches to ...

The new generation of analgesics and antiinflammatory drugs, namely, the selective inhibitors of cyclooxygenase–2 (COX-2) enzymes, popularly known as Coxibs, have become a very popular class of drugs because of their gastro-sparing property. Coxibs were the widely prescribed drugs (nearly 8 million people round the globe take these drugs) until the recent setback with rofecoxib, which was withd...

Abstract--Acute oral doses of neutralized 2-N-ethylaminoethanol (EAE) in rats greatly increased gastric secretion, resulting in dehydration and death after 3-4 days. The effect of EAE on gastric secretion did not appear to be due to osmotic effects or to histopathological changes in the gastro-intestinal tract. Short-term administration of neutralized EAE in the drinking water produced evidence...

aqueous (hydrophilic) and chloroform (lipophilic) extracts of nine medicinal plants currently used in traditional medicine, in egypt, to treat some gastrointestinal tract (git) disorders were tested for their gastro-protective effect against the incidence of peptic ulcer. indomethacin-induced ulcer in a rat model was used for this testing. mentha microphylla, brassica oleracea capitata (cabbage...

gastro-esophageal reflux disease (gerd) regularly occurs when stomach acid moves up from the stomach into the esophagus. gerd might be associated with chronic asthma symptoms such as coughing and breathlessness. according to several studies on children and adults, gerd is proven to have a close relationship with asthma.  medication treatment via proton-pump inhibitors (ppis), such as omeprazole,...