The endoscopic diagnosis of hiatal hernia (sliding type) relies on direct and indirect criteria during the oesophagoscopic or gastroscopic approach. A wide separation between the anatomic and mucosal oesophago-gastric junction, the presence of a so-called Schatzki-ring, a wandering junction with sliding gastric mucosal folds during inspiration and two ringlike structures are important. Whereas ...

about 1.5-6 % of the patients with gastric and duodenal erosions admitted to i.c.u. are prone to gastrointestinal (g.i.) bleeding with its ensuing complications. routine prophylaxis with h2-blockers and anti-acid has been used in these high risk patients for decades. in this study we evaluated the effect of p.o omeprazole, a potent acid inhibitor with prolong effects on gastric ph.  patients wi...

BACKGROUND Obesity is an important risk for pathological gastroesophageal reflux. AIM To assess the effects of gastric bypass on obese subjects with erosive esophagitis. PATIENTS AND METHODS Sixty two morbid obese subjects (aged 16 to 70 years, 41 females) with erosive esophagitis at the moment of surgery were studied. These patients were subjected to a gastric bypass with gastric resection...

BACKGROUND Upper gastrointestinal (GI) bleeding is a common medical emergency associated with significant morbidity and mortality. The clinical presentation depends on the amount and location of hemorrhage and the endoscopic profile varies according to different etiology. At present, there are limited epidemiological data on upper GI bleed and associated mortality from India, especially in the ...

Background Dyspepsia is a common presentation for many patients in gastroenterology clinics. Helicobacter pylori (H. pylori) infection is endemic in many countries around the world and its relation to dyspepsia has long been questioned. This study aimed at comparing demographic, endoscopic and histologic features among dyspeptic patients with and without stool H. pylori antigen positivity. Me...

BACKGROUND AND AIMS Factors predisposing to endoscopic ulcer formation or healing with non-steroidal anti-inflammatory drugs (NSAIDs) have not been well defined. METHODS We used multivariate analysis of data from three large similar trials to identify factors associated with endoscopic lesions and healing. We compared the effectiveness of omeprazole 20 mg and 40 mg daily, misoprostol 200 micr...

Background and aims: Factors predisposing to endoscopic ulcer formation or healing with non-steroidal anti-inflammatory drugs (NSAIDs) have not been well defined. Methods: We used multivariate analysis of data from three large similar trials to identify factors associated with endoscopic lesions and healing. We compared the effectiveness of omeprazole 20 mg and 40 mg daily, misoprostol 200 μg f...

This study aimed comparison the gastric ulcer induced by indomethacin, aspirin, and ethanol on level of pathological changes, ulcers surface area, index. Forty rats were divided into 4 groups: control group received normal saline, remaining groups, Indomethacin 40 mg/kg, Aspirin group100 80% 5 ml/kg, all doses orally administrated one time. The result revealed had largest whereas indomethacin a...

Cameron lesions are linear gastric ulcers or erosions on the mucosal folds at the diaphragmatic impression in patients with a large hiatal hernia. The clinical relevance of Cameron lesions is due to their potential complications such as gastrointestinal bleeding (acute, chronic and obscure) and anemia. The diagnosis is usually made during upper endoscopy. Medical therapy is the mainstay of trea...