We describe the characterization of a chip-based platform (3(D)-KITChip) for the three-dimensional cultivation of cells under perfusion conditions via magnetic resonance imaging (MRI). Besides the chip, the microfluidic system is comprised of a bioreactor housing, a medium supply, a pump for generating active flow conditions as well as a gas mixing station. The closed circulation loop is ideall...

The objective of this study was to investigate the hydrodynamics and gas-liquid mass transfer coefficient an external-loop airlift reactor (ELAR). ELAR operated in three cases: different inlet velocities fluids, alcohols solutions (water, 0.5% methanol, ethanol, propanol butanol) concentration methanol (0%, 0.5%, 1%, 2% 5%). influence superficial gas velocity various diluted alcohol on studied....

a dissolved methane sensor based on silicone tube was designed, constructed and optimized.the silicone tube diameter, silicone tube length and helium flow rate (as the carrier gas(were considered as process parameters to be optimized.a continuous stream of helium (50 ml/min) was directed through the tubing, sweeping out the dissolved methane which diffused through the walls of the tubing from t...

−Bacterial cellulose (BC) was produced by Acetobacter xylinum KJ1 in a modified airlift-type bubble column bioreactor, which had a low shear stress and high oxygen transfer rate (kLa). Saccharified food wastes (SFW) were used as the BC production medium due to its low cost. An aeration rate of 1.2 vvm (6 L/min) was tentatively determined as the optimal aeration condition in a 10 L spherical typ...

Extended abstract Understanding the complexity of the fluid dynamics in bubble column and airlift reactors is important due to their application in the chemical and bioprocess industries. So the objective of this research was to develop a fundamental understanding of the hydrodynamics and interactions with the chemistries involved in the bubble column reactor to maximize overall efficiency for ...