Desmoid tumors are uncommon benign neoplasm of the fibroblasts. They occur rarely in the general population, but they are comparatively common in patients with familial polyposis coli with or without other elements of Gardner's syndrome. Herein, we report a 16-year-old woman with Gardner's syndrome complicated by desmoid tumors on the right subscapular area.

Nine unusual bleeding and clotting disorders (or mimickers of such) are described in the format of case presentations, with focus on clinical history, images and diagnostic tests, followed by a discussion of the disease itself and a summarizing clinical teaching point. The disease entities discussed are acquired factor VIII inhibitor, acquired von Willebrand factor inhibitor, haemophilic pseudo...

HE tumorous head (tu-h) abnormality and genetic mechanism were disTcussed by GARDNER (1948), GARDNER and WOOLF (1949) and NEWBY ( 1949). Penetrance, expressivity and relative viability were investigated by GARDNER and RATTY (1952). The influence of high and low temperatures on the expression was described by GARDNER and WOOLF (1950). Modifiers and alleles of tumorous head genes were found in la...

Dental anomalies are common congenital malformations that can occur either as isolated findings or as part of a syndrome. This review focuses on genetic causes of abnormal tooth development and the implications of these abnormalities for clinical care. As an introduction, we describe general insights into the genetics of tooth development obtained from mouse and zebrafish models. This is follow...