Leukotriene B4 12-hydroxydehydrogenase (LTB4DH) catalyzes the oxidation of proinflammatory LTB4 into less bioactive 12-oxo-LTB4. We recently discovered that LTB4DH was induced by two different natural products in combination. We previously isolated gallic acid from Radix Paeoniae through a bioactivity-guided fractionation procedure. The purpose of this study is to test the hypothesis that LTB4D...

Vimang is a standardized extract derived from Mango bark (Mangifera Indica L.), commonly used as anti-inflammatory phytomedicine, which has recently been used to complement cancer therapies in cancer patients. We have further investigated potential anti-tumour effects of glucosylxanthone mangiferin and indanone gallic acid, which are both present in Vimang extract. We observed significant anti-...

The molecularly imprinted polymers for gallic acid were synthesized by precipitation polymerization. During the process of synthesis a non-covalent approach was used for the interaction of template and monomer. In the polymerization process, gallic acid was used as a template, acrylic acid as a functional monomer, ethylene glycol dimethacrylate as a cross-linker and 2,2'-azobisisobutyronitrile ...

BACKGROUND Myocardial infarction is one of the important causes of death during old ages. Gallic acid as an antioxidant or cyclosporine A (CsA) as inhibitor of mitochondrial permeability transition pore (mPTP) alone could prevent these complications to some extent, but their combination effect has not been investigated. OBJECTIVES The aim of this study was to determine the combined effect of ...

IN THE TITLE COMPOUND (SYSTENATIC NAME: 3,4,5-trihy-droxy-benzoic acid pyridine monosolvate), C(5)H(5)N·C(7)H(6)O(5), the gallic acid mol-ecule is essentially planar (r.m.s deviation = 0.0766 Å for non-H atoms) and is linked to the pyridine mol-ecule by an O-H⋯N hydrogen bond. An intra-molecular O-H⋯O hydrogen bond occurs in the gallic acid mol-ecule. The gallic acid and pyridine mean planes ma...

High yield and fast extraction performance ability with less solvent consumption and protection offered to thermo labile constituents are some of the attractive features of this new promising microwave-assisted extraction (MAE) technique. Therefore, MAE of gallic acid in the leaves of Eucalyptus x hybrida Maiden has been carried out and precise HPTLC method was developed for quantitative analys...

Introduction 1.1.20) catalyze the hydrolysis of ester and depside bonds in tannic acid [1], the reaction end products is glucose and gallic acid [2,3]. The enzyme is utilized in a number of industrial applications, is extensively used in wine, beer, coffee flavored soft drinks [4] and also including the manufacture of instant tea [5]. In addition gallic acid, finds use in the dye making, and le...

In a new approach to microbial gallic acid production by Aspergillus fischeri MTCC 150, 40gL(-1) of tannic acid was added in two installments during the bioconversion phase of the process (25gL(-1) and 15gL(-1) at 32 and 44h respectively). The optimum parameters for the bioconversion phase were found to be temperature: 35°C, pH: slightly acidic (3.3-3.5), aeration: nil and agitation: 250 rpm. A...

To establish the method for qualitative and quantitative determination of gallic acid in Herba Gei. Gallic acid content is determined by HPLC with Diamonsil C18 column as the stationary phase, under the conditions of methanol-0.1% phosphoric acid in water (10:90) mobile phase, 271 nm detection wavelength, and 40°C column temperature. Peak area of gallic acid shows a good linearity with the inje...