background: one million people are diagnosed with gastric cancer (gc) annually and the prognosis for patients with advanced gc or gastroesophageal junction (gej) cancer is usually poor with a median survival time of 8 to 10 months. recent reports have identified that anti her2 target therapy improved the median survival rate in patients with her2 positive gc; but a wide range of her2 overexpres...

1. The blood-brain barrier is essential for the maintenance and regulation of the neural microenvironment. The main characteristic features of blood-brain barrier endothelial cells are an extremely low rate of transcytotic vesicles and a restrictive paracellular diffusion barrier. 2. Endothelial blood-brain barrier tight junctions differ from epithelial tight junctions, not only by distinct mor...

Holliday junctions are critical intermediates for homologous, site-specific recombination, DNA repair, and replication. A wealth of structural information is available for immobile four-way junctions, but the controversy on the mechanism of branch migration of Holliday junctions remains unsolved. Two models for the mechanism of branch migration were suggested. According to the early model of Al...

Holliday junctions are critical intermediates for homologous, site-specific recombination, DNA repair, and replication. A wealth of structural information is available for immobile four-way junctions, but the controversy on the mechanism of branch migration of Holliday junctions remains unsolved. Two models for the mechanism of branch migration were suggested. According to the early model of Al...

Using a perturbative approach to simple model systems, we derive useful propensity rules for inelastic electron tunneling spectroscopy (IETS) of molecular wire junctions. We examine the circumstances under which this spectroscopy (that has no rigorous selection rules) obeys well defined propensity rules based on the molecular symmetry and on the topology of the molecule in the junction. Focusin...

Graphitic carbon nitride (g-C3N4), as the one of most promising photocatalysts, usually relies on noble metal co-catalysts in photocatalytic water splitting H2 evolution process, which greatly increases use cost. Here, a zeolite imidazole framework (ZIF-67) derived [email protected]/g-C3N4 composite was constructed through facile thermal condensation ZIF-67 and melamine. The obtained composites...

The effect of a long-term treatment (one to two years) with cimetidine (1.6 g per day) and an antacid (Regla pH) was evaluated in nine patients with a Barrett's oesophagus. The results showed that such long-term treatment had a beneficial effect on the symptoms and endoscopic signs of oesophagitis and on the healing of a Barrett's ulcer, but did not result in a regression of the squamocolumnar ...

Au algorithm is developed for findiug a close to optimal junction tree of a given graph Tile algorithm has a worst case co~nplexity O(ckn~) where a and c are coustants, the nmnber of vertices, and k is largest clique in a juuction tree of G in which this size is mini~nized. The algorithm guarantees that the logarittHn of the size of the state space of the heaviest clique in the junction tree pr...

conclusions the outside diameter/inside diameter ratio at the metaphyseal/diaphyseal junction of the distal radius on ap radiographs is suitable for use as a predictor of distal-radius bone density. further studies should be performed, and clinical utility evaluated. results the mean bmd was 0.559 (sd = 0.236) g / cm2. the mean outside diameter/inside diameter ratio was 1.24 (sd = 0.013); the r...