The present investigation was undertaken to clinically and radiograplu’caily observe human p~mary teeth after pulpotomy using one-fifth dilution of formocresol. Seventyseven teeth of 59 ctuTdren, average age seven years, were treated. Seventy teeth were available for follow-up over a peHod varying from 4 to 36 months. The degree of root resorption was evaiuated comparing pairs of treated and ho...

Context: This article reviews the available evidence about the barrier membranes utilized in Guided Tissue Regeneration process to prevent the migration of unfavorable cells to the wound area. Evidence Acquisition: Available evidence about membranes properties and their different uses were reviewed, and the results of clinical and animal studies and systematic reviews were gathered. Results: A ...

This study compared the effectiveness of 2 barrier membranes, expanded polytetrafluoroethylene (e-PTFE) and collagen, in treating Class II furcation defects of mandibular molars in humans. Seventeen nonsmoking subjects with no history of systemic disease each presenting with Class II furcation defects in 2 mandibular molars were selected and underwent initial therapy. At the time of the surgery...

The purpose of this report is to describe the histopathology of radiolucent lesions associated with pulp necrosis in primary molars. Twenty-one carious, previously untreated, primary molars with radiolucent lesions were extracted with forceps under local anesthesia. If a lesion remained attached to the root, the specimen was transferred to 10% neutral buffered formalin. The sockets were gently ...

OBJECTIVE To determine the effects of autologous fibrinogen (AF) and absorbable barrier membrane (ABM) on periodontal healing of canine experimental grade-III furcation defects. ANIMALS 18 conditioned, laboratory-source, adult Beagles. PROCEDURE Defects were developed bilaterally at the second and fourth premolars and maintained for 12 weeks. Defects were treated with AF, ABM, AF and ABM, o...

* Post-Doctoral Student, Department of Microbiology, Dental Research Institute, São Leopoldo-Mandic. ** Professor and Chairman, Department of Oral Pathology, School of Dentistry, University of São Paulo. *** Doctor of Dental Medicine, Private Practice, Fairhope, USA. **** Professor and Chairman, Department of Periodontology, School of Dentistry, State University of Campinas. ***** Doctor of Den...

Molecular interactions between epithelium and mesenchyme are important for root formation. Nuclear factor I-C (Nfic) has been identified as a key regulator of root formation. However, the mechanisms of root formation and their interactions between Hertwig's epithelial root sheath (HERS) and mesenchyme remain unclear. In this study, we investigated the role of Nfic in root patterning and growth ...

This study aimed to observe the regenerative effect of brain-derived neurotrophic factor (BDNF) in a non-human primate furcation defect model. Class II furcation defects were created in the first and second molars of 8 non-human primates to simulate a clinical situation. The defect was filled with either, Group A: BDNF (500 µg/ml) in high-molecular weight-hyaluronic acid (HMW-HA), Group B: BDNF...