abnormalities of the thyroid gland are among the most frequent endocrine complications observed in childhood cancer survivors. we report an 11 years old girl who developed central hypothyroidism and acth deficiency during the chemotherapy for cns relapse of acute lymphoblastic leukemia before receiving radiotherapy. keywords: thyroid gland, hypothyroidism, chemotherapy, acute lymphoblastic leuk...

administration of a precise amount of activity in thyroid gland radioiodine (¹³¹i) therapy is of prime importance. several methods for this purpose have been suggested and used over many years. in this paper, a method for required ¹³¹i activity calculation for each case has been proposed. major factors affecting ¹³¹i calculation such as gland volume, integral dose, and prescription index have b...

Abnormalities of the thyroid gland are among the most frequent endocrine complications observed in childhood cancer survivors. We report an 11 years old girl who developed central hypothyroidism and ACTH deficiency during the chemotherapy for CNS relapse of acute lymphoblastic leukemia before receiving radiotherapy. Keywords: Thyroid gland, hypothyroidism, chemotherapy, acute lymphoblastic leu...

Deleterious mutations of SLC26A4 cause Pendred syndrome (PS), an autosomal recessive disorder comprising goitre and deafness with enlarged vestibular aqueducts (EVA), and nonsyndromic hearing loss (NSHL). However, the SLC26A4 hyperactivity was recently associated with the emergence of autoimmune thyroid diseases (AITD) and asthma among human and mouse model. Here, by direct sequencing, we inves...

INTRODUCTION Parathyroid incidentaloma (PTI) designates a nodule discovered incidentally during thyroid sonography, and whose location and aspect suggests an abnormal parathyroid. Our aim was to assess the prevalence of PTI, their functional characteristics and to identify the factors correlated with their presence. PATIENTS AND METHODS We recorded all patients detected with PTI between Janua...

echinococcosis, although eradicated in many countries, is still widespread in communities where agriculture is dominant. cystic hydatidosis is a significant public health problem in the regions with endemic echinococcosis. the hydatid cysts tend to form in the liver or lung, but may also be found in other organs of the body such as brain, heart, and bone, while thyroid gland involvement is rath...

Background  It is remain a main concern that pediatric chest radiographies contribute to the significant radiation exposure to the thyroid gland as a more susceptible organ to radiation induced cancer. The aim of this study was to evaluate the entrance surface dose (ESD) of pediatric chest radiography compared to the diagnostic reference levels (DRL) and evaluation the efficacy of the lead (Pb)...

nomously functioning thyroid nodule 505 InTROduCTIOn Diagnostic procedures for thyroid disorder include bio chemical evaluation: measurement of serum thyrotropin (TSH), free thyroid hormone (free thyroxine [FT4], free triiodothyronine [FT3]) and thyroid antibody levels, as well as imaging including ultrasonography (USG) and thyroid scan. In some cases fine needle aspiration bio psy (FNAB) shoul...

Isolated metastases to the thyroid gland are rare. It is not common for lung cancer metastasize gland, and when it metastasizes; predominant pathology usually adenocarcinoma. In this article, a rare case of metastasis from squamous cell presented. A forty-four-year-old male patient diagnosed with Stage III in our clinic. After chemotherapy, nodular lesion detected. Through fine needle aspiratio...

The occurrence of hypercholesterolemia, lowered basal metabolic rate and depressed serum proteinbound iodine in the nephrotic syndrome has directed attention to the thyroid gland in this disorder. Although hypothyroidism has been suspected, these patients are usually considered, on clinical grounds, to be euthyroid, and they fail to respond in a specific manner to even large doses of thyroid ho...