AIM To assess serum myeloperoxidase (MPO) levels in autistic children with severe gastrointestinal (GI) disease and to test the hypothesis that there is an association between serum MPO concentration and inflammatory GI disease, including antineutrophil cytoplasmic antibodies (ANCA), previously seen in a subgroup of autistic children. SUBJECTS AND METHODS Serum from 40 autistic children with ...

One of the most common problems in autistic children is split attention. Split attention prevents autism children from being able to focus attention on their learning, and tasks. As a result, it is important to identify how to make autistic individuals focus attention on learning. Considering autistic individuals have higher visual abilities in comparing with ordinary people, visual supports ar...

AIM Deficiency of Alpha-1-antitrypsin (AAT) can be a genetic condition that increases the risk of developing liver, lung and possibly gastrointestinal disease. Since many autistic children also have gastrointestinal disorders, this study was designed to measure serum concentration of AAT and establish AAT genotypes in autistic children, age and gender matched non-autistic siblings, parents and ...

Previous studies show that autistic children fail tests of second-order belief attribution. They also fail tests of lying and deception. The present study used Leekam's (1988) joke-lie distinction task to test (a) understanding of second-order mental states (intention and belief) and (b) the ability to judge these acts as lies or jokes. Seventeen normal and 16 autistic children took part. Eight...

With regard to the increase of autism among children, it is possible to save autistic children via recognizing the required spaces and therapeutic centers for the autistic children. Unfortunately, there are not such places in Iran. The purpose of making such centers is to support the social services development for autism and support families of the autistic children. It also intends to gather ...

Autism is a neurodevelopmental syndrome characterized by impaired social and executive functions. Functional magnetic resonance imaging (fMRI) is a non-invasive technique that allows investigation of the neural networks underlying cognitive impairments in autism. In this article, brain imaging studies investigating the functional brain anatomy of autism are reviewed. Face recognition, theory of...

The aim of this study was to evaluate anxiety, depression, alexithymia, and general psychological symptoms in the mothers of autistic children in comparison with those in the mothers of mentally retarded children. Forty mothers of autistic children and 38 mothers of mentally retarded children were included in the study. After a clinical interview, psychometric tests were performed for depressio...

High proportions of autistic children suffer from gastrointestinal (GI) disorders, implying a link between autism and abnormalities in gut microbial functions. Increasing evidence from recent high-throughput sequencing analyses indicates that disturbances in composition and diversity of gut microbiome are associated with various disease conditions. However, microbiome-level studies on autism ar...