نتایج جستجو برای: fucoxanthin

تعداد نتایج: 479  

Journal: :Acta biochimica Polonica 2016
Wiktor Tokarek Stanisław Listwan Joanna Pagacz Piotr Leśniak Dariusz Latowski

Fucoxanthin, diadinoxanthin and diatoxanthin are carotenoids found in brown algae and most other heterokonts. These pigments are involved in photosynthetic and photoprotective reactions, and they have many potential health benefits. They can be extracted from diatom Phaeodactylum tricornutum by sonication, extraction with chloroform : methanol and preparative thin layer chromatography. We asses...

Breast cancer is the most common cancer type among women all over the world. Chemotherapy is the use of anticancer medicines for treating cancer but it has many side effects and cells may become resistant to these chemical medicines. Therefore, finding new compounds of natural origin could be a promising solution to this problem. The aim of the current study was to evaluate anticancer activity ...

2005
Huan Zhang Debashish Bhattacharya Senjie Lin

Despite their evolutionary and ecological importance, dinoflagellate phylogeny remains poorly resolved. Here we explored the utility of mitochondrial cytochrome b (cob) in inferring a dinoflagellate tree and focused on resolving the relationship between fucoxanthin-and peridinin-containing taxa. Trees were inferred using cob and small subunit rDNA alone or in combination as concatenated data an...

Journal: :Pharmaceutical Sciences 2022

Background: The development of multidrug resistance (MDR) is a major barrier to achieving effective chemotherapy in cancer. Studies have shown that epithelial ovarian cancer initially responds platinum-based therapy, however, the recurrent type often resistant treatment and associated with high mortality. Fucoxanthin, natural component found marine algae, possesses various pharmacologic propert...

Journal: :Carcinogenesis 1998
J M Kim S Araki D J Kim C B Park N Takasuka H Baba-Toriyama T Ota Z Nir F Khachik N Shimidzu Y Tanaka T Osawa T Uraji M Murakoshi H Nishino H Tsuda

The present study was carried out to examine the chemopreventive effects of carotenoids such as fucoxanthin, lycopene and lutein as well as curcumin and its derivative, tetrahydrocurcumin (THC), on development of putative preneoplastic aberrant crypt foci (ACF) in colons of mice initiated with 1,2-dimethylhydrazine dihydrochloride (DMH). Influence on proliferation of colonic crypt epithelial ce...

2010
Jidnyasa Joshi-Deo Matthias Schmidt Ansgar Gruber Wolfram Weisheit Maria Mittag Peter G. Kroth Claudia Büchel

Fucoxanthin chlorophyll proteins (Fcps), the light-harvesting antennas of heterokont algae, are encoded by a multigene family and are highly similar with respect to their molecular masses as well as to their pigmentation, making it difficult to purify single Fcps. In this study, a hexa-histidine tag was genetically added to the C-terminus of the FcpA protein of the pennate diatom Phaeodactylum ...

Journal: :Biochemical and biophysical research communications 2005
Hayato Maeda Masashi Hosokawa Tokutake Sashima Katsura Funayama Kazuo Miyashita

Mitochondrial uncoupling protein 1 (UCP1) is usually expressed only in brown adipose tissue (BAT) and a key molecule for metabolic thermogenesis to avoid an excess of fat accumulation. However, there is little BAT in adult humans. Therefore, UCP1 expression in tissues other than BAT is expected to reduce abdominal fat. Here, we show reduction of abdominal white adipose tissue (WAT) weights in r...

2013
Ae Wha Ha Woo Kyoung Kim

This study determined the effects of fucoxanthin on gene expressions related to lipid metabolism in rats with a high-fat diet. Rats were fed with normal fat diet (NF, 7% fat) group, high fat diet group (HF, 20% fat), and high fat with 0.2% fucoxanthin diet group (HF+Fxn) for 4 weeks. Body weight changes and lipid profiles in plasma, liver, and feces were determined. The mRNA expressions of tran...

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