N-Acetylmuramyi-L-alanyl-D-isoglutamine (muramyl dipeptide, MDP) 1 was shown (1) to be the minimal and essential s t ructure requi red for adjuvant activity o f bacterial cell wall peptidoglycans. Fur ther , MDP has been found to possess various biological activities, o ther than adjuvant activity, that are exer ted by bacterial cell wall peptidoglycans. Since MDP is such a potent immunomodula ...

N-Acetylmuramyi-L-alanyl-D-isoglutamine (muramyl dipeptide, MDP) 1 was shown (1) to be the minimal and essential s t ructure requi red for adjuvant activity o f bacterial cell wall peptidoglycans. Fur ther , MDP has been found to possess various biological activities, o ther than adjuvant activity, that are exer ted by bacterial cell wall peptidoglycans. Since MDP is such a potent immunomodula ...

AIM:To observe the effect of acupuncture and moxibustion on the expression of IL-1beta and IL-6 mRNA in ulcerative colitis rats.METHODS:The SD rat ulcerative colitis model was created by immunological method associated with local stimulation. Colonic mucosa was prepared from human fresh surgical colonic specimens, homogenized by adding appropriate amount of normal saline and centrifuged at 3000...