Isoquinoline alkaloids are a large class of compounds derived from the amino acid L-tyrosine containing many physiologically active members. Among the isoquinoline alkaloids, morphine is one of the pharmaceutically important members that is still derived from the plant that produces it, the opium poppy Papaver somniferum. P. somniferum produces over 80 alkaloids derived from L-tyrosine. We have...

-   ahmadi, m., kaboli, m., imani harsini, j., khosravi sharifabadi, r., almasi, m., 2012. strategic management plan for wolf (canis lupus) in hamedan province: an approach to reducing human-wolf conflicts. journal of natural environment, iranian journal of natural resources. 65, 271–281. -   ballard, w.b., dau, j.r., 1983. characteristics of gray wolf, canis lupus, den and rendezvous sites in ...

•The brain harbors distinct parenchymal and perivascular macrophages.•Binary split Cre transgenesis allows differential imaging translatome retrieval.•Cx3cr1ccre: Sall1ncre mice specifically target microglia.•Cx3cr1ccre: Lyve1ncre a subset of macrophages. The developmental molecular heterogeneity tissue macrophages is unravelling, as are their diverse contributions to physiology pathophysiology...

We investigated what factors would be related to students’ achievement in mathematics courses offered at a virtual high school. This was an attempt to understand why some succeed and some do not as well as to suggest what should be done to help with student success. Seventy-two students responded to a self-report survey on motivation (ie, selfefficacy, intrinsic value), mathematics achievement ...

The alternative economies of the Ecoxarxes (eco-networks) are created by autonomous networks like-minded groups that use social currency and mutual support practices for producing exchanging goods, services knowledge in Spanish region Catalonia. Drawing on ethnographic research, we show these commoning projects aim to establish sustain predominantly framed as fostering cooperation, aid commons....

•An interlayer synergistic binding mode for Pd recognition is achieved in a COF•COF-TzDa shows ultrahigh uptake selectivity and capacity toward Pd•One-round enrichment purification of from the nuclear waste realized Separation palladium isotopes used fuel high significance but faces notable challenges, due to harsh reprocessing condition with combined acidity, strong radiation, vast interfering...

Objective To investigate the clinical characteristics of otolith abnormal migration following canalith repositioning procedures(CRPs) for benign paroxysmal positional vertigo (BPPV) patients. The diagnosis, treatment and prevention approaches are also discussed. Methods Totally 356 cases of unilateral BPPV patients were treated by CRPs between January, 2010 and December, 2015. Otolith abnormal ...

Deleterious effects of Standardized Achievement Tests, such as those taken at Key Stage 2, on the emotional and physical wellbeing, educational experiences and outcomes of primary school pupils in England have recently been documented (e.g. Tymms & Merrell, 2007), yet there is a lack of empirical evidence supporting these claims. This paper reports on the outcomes of a mixed methods study, invo...

The presence of a small number of infected but transcriptionally dormant cells currently thwarts a cure for the more than 35 million individuals infected with HIV. Reactivation of these latently infected cells may result in three fates 1) death due to a viral cytopathic effect, 2) death due to immune clearance, or 3) a retreat back into latency. Uncovering the dynamics of HIV gene expression an...