BACKGROUND We present a novel method for augmenting the standard C-V flap used for nipple reconstruction with a free dermal graft which aims to improve the appearance of the nipple reconstruction, decrease loss of projection and improve patient satisfaction overall. METHODS The surgical technique for performing a free dermal graft augmentation of a CV flap is described. All patients who unde...

The copper-free click (CFC) reaction has been evaluated for its potential application to in vivo pre-targeting for PET imaging. A promising biodistribution profile is demonstrated when employing [(18)F]2-fluoroethylazide ([(18)F]1) and optimisation of the CFC reaction with a series of cyclooctynes shows that reactions proceed efficiently with tantalizing opportunities for application-specific t...

BACKGROUND Free flap surgery for head and neck defects has gained popularity as an advanced microvascular surgical technique. The aims of this study are first, to determine whether the known risk factors such as comorbidity, tobacco use, obesity, and radiation increase the complications of a free flap transfer, and second, to identify the incidence of complications in a radial forearm free flap...

the coverage of soft- tissue defects of the hand specially volar side needs special consideration. although certain local flaps have been described and used for resurfacing the palm, extensive injury requires distant or free flaps for coverage. abdominal pedicle flap has been traditionally used for extensive hand injuries, however there is no doubt that one of the ideal tissues for resurfacing ...

the distal third of the tibia, ankle and heel area is difficult to reconstruct. for small to medium size defects, local flaps are often an easier alternative than free flap. in lower limb surgery, the sural flap is based on this principle and this flap is becoming increasingly popular. the distally based superficial sural artery flap, first described as a distally based neuro skin flap by masqu...

Severe upper extremity injuries are considered a potential source of significant disability. Appropriate soft tissue restoration is an essential component of any treatment protocol and often requires a vascularized flap to protect the neurovascular and musculo-tendinous structures. The use of latissimus dorsi muscle or myocutaneous flap is considered in ideal solution in such conditions as it p...

BACKGROUND The purpose of this study was to compare postoperative morbidities and functional outcomes of pectoralis major myocutaneous (PMMC) flap and cutaneous free flap reconstruction approaches in hypopharyngeal squamous cell carcinoma patients. METHODS We retrospectively reviewed records from 99 patients who underwent hypopharyngeal reconstruction with a cutaneous free flap (n=85) or PMMC...

introduction: reconstruction of intraoral soft tissue defects is important in restoring function and esthetic. in large defects, there will be demand for regional pedicle flaps or free flaps. hard palate separates nasal and oral cavities. due to the small surface area between flap and remaining palate after surgical resections, optimal blood supply of the flaps for hard palate reconstructions a...