background: discovery of short cell free fetal dna (cffdna) fragments in maternal plasma has created major changes in the field of prenatal diagnosis. the use of cffdna to set up noninvasive prenatal test is limited due to the low concentration of fetal dna in maternal plasma therefore, employing a high efficiency extraction method leads to more accurate results. the aim of this study was to ev...

We evaluate the free energy of the random cluster model at its critical point for 0 < q < 4 using an exact result due to Baxter, Temperley and Ashley, and obtain an explicit expression in the form of an infinite series. It is found that the resulting series expression assumes a form which depends on whether or not π/2 cos−1( √ q/2) is a rational number. As a by-product, our consideration leads ...

Over the past years, DNA biosensors have been developed to analyze DNA interaction and damage that have important applications in biotechnological researches. The immobilization of DNA onto a substrate is one key step for construction of DNA electrochemical biosensors. In this report, a direct approach has been described for immobilization of single strand DNA onto carboxylic acid-functionalize...

background: alpinia galanga l. belonging to the family zingiberaceae is widely grown in the state of kerala, india. they are effective antioxidant and free radical scavenger under both in vitro and in vivo condition. the efficacy of the isolated flavonoids in conferring protection from radiation induced damages to genomic dna was studied. materials and methods: the bioflavonoids, galangin and k...

Cell-free DNA has emerged as the most reliable, non-invasive prenatal screening tool for fetal aneuploidies. It come to replace previously widely used quadruple screen offered in second trimester of pregnancy. This change comes with improved detection aneuploidy but also presents potential gaps diagnosis including open defects and emerging data on prediction adverse pregnancy outcomes. review a...