A method for the first-order analysis of the point registration problem is presented and validated. The method is a unified approach to the problem that allows for inhomogeneous and anisotropic fiducial localization error (FLE) and arbitrary weighting in the registration algorithm. Cross-covariance matrices are derived both for target registration error (TRE) and for weighted fiducial registrat...

BACKGROUND There is a need for a clinically useful, quantitative index for measurement of disease activity in cats with chronic enteropathy (CE). OBJECTIVE To develop a numerical activity index that is of practical value to clinicians treating CE in cats. ANIMALS Eighty-two cats with CE. METHODS Retrospective case review of 59 cats diagnosed with inflammatory bowel disease (IBD). Prospect...

Fiducial-based rigid registration is the preferred method for aligning the preoperative image with the intra-operative physical anatomy in existing image-guided surgery systems. After registration, the targets locations usually cannot be measured directly, so the Target Registration Error (TRE) is often estimated with the Fiducial Registration Error (FRE), or with Fitzpatrick TRE (FTRE) estimat...

Fibroblast growth factor 2 (FGF2), a member of the FGF family, positively regulates bone formation and osteoblast differentiation. Bone sialoprotein (BSP) is highly expressed during early bone formation and may play a role in primary mineralization of bone. In the present study, FGF2 (10 ng/mL) was found to increase the levels of Runx2 and BSP mRNA at 3 and 12 h in human osteoblast-like Saos2 c...

with impervious exteriors, such as shells or chitinous exoskeletons. Advantages to this method are high throughput, high success rate and enough template DNA for several different assays (FRE-PCR used only 5 μL of the 20-μL supernatant). Other extraction methods that were tried and discarded for low success rates included boiling in water or PCR buffer, grinding before boiling, grinding with co...

Caring for patients with leg ulcers continues to be a challenge for healthcare professionals, particularly since the current healthcare climate of an ageing population, increased incidences of obesity and diabetes, as well as other comorbidities can complicate their management (Todd, 2014). It is estimated that 1% of the population suffer from leg ulcers at some point in their lives (Callam, 19...

One in every three people the world still lacks access to clean drinking water. Aside from microbiological pollution, high fluoride content water is one of most serious problems African countries. This study aimed contribute availability by developing a point-of-use purifier using an aluminum oxide-based flocculent-disinfectant composite. Batch experiments were conducted determine factors affec...

Abstract Currently, patients use the Internet for health information relating to surgery. The aim of this study is assess readability and quality online acromioclavicular joint reconstruction. We hypothesise that will be poor too difficult read average patient. top 50 results from Google, Bing, Yahoo (MeSH “acromioclavicular reconstruction”, “ac reconstruction”) were used analysis. Readability ...

Background: Studies of deep brain stimulation (DBS) require accurate electrode localization and image registration. We used anatomical fiducials to investigate registration errors in patients who underwent subthalamic nucleus (STN) DBS for Parkinson’s disease (PD). Methods: conducted a retrospective analysis bilateral STN PD. Pre post operative MRI scans were non-linearly normalized standard te...

Reputation effects and other-regarding preferences have each been used to predict cooperative outcomes in markets with inefficient equilibria. Existing reputationbuilding models require either infinite time horizons or publicly observed identities, but cooperative outcomes have been observed in several moral hazard experiments with finite horizons and anonymous interactions. This paper introduc...