background: nephrotoxicity is one of the major side-effects of cisplatin that has been seen in about 20% of treated patients. the aim of this study was to assess the effectiveness of a forced hydration protocol comprised of isotonic saline, potassium chloride (kcl) and magnesium sulfate (mgso4) on prevention of cisplatin nephrotoxicity. methods: this cross sectional prospective study was perfor...

Despite improved prognosis for patients with cystic fibrosis (CF), they continue to suffer from progressive decline in pulmonary function and exercise tolerance. Beyond puberty, female patients have greater loss of pulmonary function and higher mortality than males, yet no one has studied male-female differences in exercise tolerance among patients. We therefore compared the responses to progre...