نتایج جستجو برای: fndc5

تعداد نتایج: 325  

2015
Natalia Wawrusiewicz-Kurylonek Beata Telejko Mariusz Kuzmicki Angelika Sobota Danuta Lipinska Justyna Pliszka Beata Raczkowska Pawel Kuc Remigiusz Urban Jacek Szamatowicz Adam Kretowski Piotr Laudanski Maria Gorska Rudolf Kirchmair

AIM The aim of the study was to compare maternal and cord blood levels of betatrophin--a new peptide potentially controlling beta cell growth--as well as in its mRNA expression in subcutaneous adipose tissue, visceral adipose tissue and placental tissue obtained from pregnant women with normal glucose tolerance (NGT) and gestational diabetes (GDM). METHODS Serum betatrophin and irisin concent...

Skeletal muscles play an active role in regulating the metabolic homeostasis through their ability for relating to adipose tissue and endocrine hormones. Contraction of the skeletal muscle leads to increased release of several myokines, such as irisin, which is able to interact with the adipose tissue. Physical activity promotes the irisin mechanism by augmenting the peroxisomes (PGC1-α) in the...

2014
Rebecca L. Scalzo Garrett L. Peltonen Gregory R. Giordano Scott E. Binns Anna L. Klochak Hunter L. R. Paris Melani M. Schweder Steve E. Szallar Lacey M. Wood Dennis G. Larson Gary J. Luckasen Matthew S. Hickey Christopher Bell

The conversion of white adipose to the highly thermogenic beige adipose tissue has been proposed as a potential strategy to counter the unfavorable consequences of obesity. Three regulators of this conversion have recently emerged but information regarding their control is limited, and contradictory. We present two studies examining the control of these regulators. Study 1: In 10 young men, the...

Journal: :Circulation research 2012
Jenni Laidman

Not so many years ago, most considered fat a passive recipient of our indulgence. But since the discovery of leptin in 1994,1 it has become ever clearer that fat is more than a storage site for excess calories. Rather, fat plays an active, communicative role in metabolism that research is beginning to uncover. Two recent studies not only represent our rapidly changing grasp of the biology of fa...

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