Fluorine (from "le fluor", meaning "to flow") is a second row element of Group 17 in the periodic table. When bound to carbon it forms the strongest bond in organic chemistry to give organofluorine compounds. The scientific field treating them, organofluorine chemistry, started before elemental fluorine itself was isolated. Applying the fruits in academia, industrial organofluorine chemistry ha...

Preparations containing organic and inorganic fluorine compounds are used for oral hygiene. Fluoride ions contained in these preparations display high bioactivity and can alter the environment of the mouth. The aim of the study was to determine the effect of preparations containing aminofluorides, commonly used in oral hygiene, on the activity of salivary cathepsin C (EC 3.4.14.1). The research...

Intensive investigations during the last years have shown that metabotropic glutamate receptors are involved in numerous neurodegenerative diseases such as M. Parkinson, M. Alzheimer and M. Huntington as well as other central nervous system disorders including neurogenic pain, epilepsy, depression and drug addiction. The neurobiological basis of these impairments is, however, still not well und...