Chronic pain is one of the most common complaints encountered by primary care clinicians. Often, patients present not with well localized pain but with diffuse and nonspecific myalgias. Fibromyalgia is the most common etiology for this type of pain. In community-based studies, 2% [1] and 1.2% to 6.2% of school-age children screened positive for fibromyalgia [2–4]. Women and girls are at higher ...

Fibromyalgia is a common chronic syndrome defined by core symptoms of widespread pain, fatigue, and sleep disturbance. Other common symptoms include cognitive difficulty, headache, paresthesia, and morning stiffness. Fibromyalgia is increasingly understood as 1 of several disorders that are referred to as central sensitivity syndromes; these disorders share underlying causes and clinical featur...

BACKGROUND Calcium and magnesium ions play a key role in the physiology of muscular contraction: changes in calcium ions concentration may be involved in the pathogenesis of fibromyalgia. Since the plasmatic levels of calcium and magnesium in fibromyalgia patients is always in the normal range, it seemed interesting to evaluate the intracellular calcium and magnesium concentration. METHODS Th...

Fibromyalgia is a disease in which postural control and balance is impaired and tendency to falls increases. The aim of this study is to detect the presence of plantar loading impairment and to evaluate the relationship between potential plantar pressure changes and clinical signs in fibromyalgia syndrome patients. Thirty-eight female fibromyalgia patients and age and gender-matched 33 healthy ...

Fibromyalgia and depression might represent two manifestations of affective spectrum disorder. They share similar pathophysiology and are largely targeted by the same drugs with dual action on serotoninergic and noradrenergic systems. Here, we review evidence for genetic and environmental factors that predispose, precipitate, and perpetuate fibromyalgia and depression and include laboratory fin...

PURPOSE To describe and evaluate somatic symptoms in patients with rheumatoid arthritis (RA) and fibromyalgia, determine the relation between somatization syndromes and fibromyalgia, and evaluate symptom data in light of the Diagnostic and Statistical Manual-5 (DSM-5) criteria for somatic symptom disorder. METHODS We administered the Patient Health Questionnaire-15 (PHQ-15), a measure of soma...

BACKGROUND Fibromyalgia is a syndrome characterized by chronic pain, fatigue, depression, and sleep disturbances. Its primary cause is unclear. Several studies have reported decreased intracellular magnesium levels in patients with fibromyalgia and have found negative correlation between magnesium levels and fibromyalgia symptoms. OBJECTIVE To gather preliminary data on whether transdermal ma...

BACKGROUND Patients of chronic pain syndromes like fibromyalgia (FMS) when subjected to spinal anesthesia are theoretically more liable to post dural puncture headache (PDPH) as they have enhanced central nervous system sensitization and decreased descending inhibition. OBJECTIVE The current study aims to verify the incidence and chronicity of PDPH in FMS patients. STUDY DESIGN Case control...

Correspondence to: Anselm Mak Abstract: Fibromyalgia is not an uncommon condition. Although the American College of Rheumatology (ACR) has devised a set of criteria to classify fibromyalgia, whether it really exists as a distinct disease entity is still under continuing debate. Undoubtedly, fibromyalgia carries significant morbidity and socioeconomic impact to societies. Effective management wi...

Background: Fibromyalgia is a clinical condition that causes wide spread severe pain, sleep problems, fatigue, and often emotional mental distress. Patients with fibromyalgia may be more sensitive to pain than others.
 Aim: This study aims screen evaluate the efficacy safety of selective serotonin reuptake inhibitors (SSRIs) in management patients fibromyalgia.
 Methods: systematic re...