نتایج جستجو برای: fibromodulin

تعداد نتایج: 210  

Journal: :Arthritis Research & Therapy 2005
Allan A Young Margaret M Smith Susan M Smith Martin A Cake Peter Ghosh Richard A Read James Melrose David H Sonnabend Peter J Roughley Christopher B Little

Osteoarthritis (OA), the commonest form of arthritis and a major cause of morbidity, is characterized by progressive degeneration of the articular cartilage. Along with increased production and activation of degradative enzymes, altered synthesis of cartilage matrix molecules and growth factors by resident chondrocytes is believed to play a central role in this pathological process. We used an ...

2013
Nathaniel A. Dyment Chia-Feng Liu Namdar Kazemi Lindsey E. Aschbacher-Smith Keith Kenter Andrew P. Breidenbach Jason T. Shearn Christopher Wylie David W. Rowe David L. Butler

The origin of cells that contribute to tendon healing, specifically extrinsic epitenon/paratenon cells vs. internal tendon fibroblasts, is still debated. The purpose of this study is to determine the location and phenotype of cells that contribute to healing of a central patellar tendon defect injury in the mouse. Normal adult patellar tendon consists of scleraxis-expressing (Scx) tendon fibrob...

Journal: :iranian biomedical journal 0
بهناز شوهانی behnaz shohani محمود اوراضی زاده mahmoud orazizadeh محمود هاشمی تبار mahmoud hashemitabar dick heinegard

background: this work aimed to show and compare the degradation time of some of cartilage extracellular matrix components using an in vitro model for cartilage degradation induced by interleukin-1 alpha. it is known that elucidation of molecular events under interleukin-1 alpha induction of bovine nasal cartilage could obtain useful data to understand more about involving mechanisms for tissue ...

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