The dispersion of nanoparticles in ordered polymer nanostructures can provide control over particle location and orientation, and pave the way for tailored nanomaterials that have enhanced mechanical, electrical, or optical properties. Here we used silk fibroin, a natural biopolymer, to embed gold NCs (nanocrystals), so as to obtain well-ordered structures such as nanowires and self-assembled t...

Silk and silk fibroin, the biomaterial from nature, nowadays are being widely utilized in many cutting-edge micro/nanodevices/systems via advanced micro/nanofabrication techniques. Herein, for the first time to our knowledge, we report aqueous multiphoton lithography of diversiform-regenerated-silk-fibroin-centric inks using noncontact and maskless femtosecond laser direct writing (FsLDW). Init...

INTRODUCTION There have been many attempts to repair full-thickness articular cartilage defects using tissue-engineering techniques, focusing particularly on the regeneration of high-strength cartilage. Unfortunately, the strength is insufficient for fixation of the grafted part on large defect of joint surface. Current focus in our laboratory has been placed on the development of a novel silk ...

The presented study aimed to design and characterize bilayer Alginate/Fibroin scaffolds provide faster higher quality treatment of skin tissue losses with engineering approach. In this context, it was tried form the dermis epidermis layers alginate salts (sodium calcium) fibroin a biomimetic approach, determine most suitable salt-fibroin composite scaffold by trying different production methods...

A previous experiment demonstrated that fibroin protein and chitosan mixed in proper proportion presented good physical and chemical properties and biological characteristics, which can make up for their respective disadvantages. To observe the growth of bone marrow mesenchymal stem cells (BMSCs) on these fibroin protein/chitosan 3D scaffolds, induced rabbit BMSCs were seeded on fibroin protein...

Bioceramic scaffolds such as silicate bioceramics have been widely used for bone tissue engineering. However, their high degradation rate, low mechanical strength and surface instability are main challenges compromising their bioactivity and cytocompatibility which further negatively affect the cell growth and attachment. In this study, we have investigated the effects of silk fibroin coating o...

Silk Fibroin-Coated Mg Implants for Bone Repair Engineering In article number 2101724, Hui Fang, Chenxi Wang, and co-workers demonstrate an effective O2/N2 hybrid plasma activation technology to modify alloy, achieving a robust organic protein/inorganic metal interface. The silk fibroin-coated implants possess significantly improved adhesion, anti-corrosion biocompatibility, which expands the b...

The objective of the present study is to investigate the possibility of preparing pure protein microspheres from regenerated silk fibroin (RSF). It is found that RSF microspheres, with predictable and controllable sizes ranging from 0.2 to 1.5 mm, can be prepared via mild selfassembling of silk fibroin molecular chains. The merits of this novel method include a rather simple production apparatu...

The synthesis of the hexanucleotide d)A-C-C-A-G-C), complementary to the 2 major triplets of fibroin mRNA, using the phosphotriester methodology is described. The protected dinucleotides ((MeO)2Tr)dbzA.anC, ((MeO)2Tr)danC.bzA and ((meO)2Tr)dacG.anC were synthesized; the latter two were detritylated and joined in stepwize fashion to the 1st to form the protected hexanucleotide ((MeO)2Tr)dbzA.anC...

Silk fibroin from the silkworm, Bombyx mori, has excellent properties such as biocompatibility, biodegradation, non-toxicity, adsorption properties, etc. As a kind of ideal biomaterial, silk fibroin has been widely used since it was first utilized for sutures a long time ago. The degradation behavior of silk biomaterials is obviously important for medical applications. This article will focus o...