Burn and disuse results in metabolic and bone changes associated with substantial and sustained bone loss. Such loss can lead to an increased fracture incidence and osteopenia. We studied the independent effects of burn and disuse on bone morphology, composition and strength, and microstructure of the bone alterations 14days after injury. Sprague-Dawley rats were randomized into four groups: Sh...

Based on the thermo elasticity, using finite element method to analyze the stress of femur-prosthesis system when the hip joint has been replaced, a reference for the selection of prosthesis material is presented after discussing the thermo physical property of material which has an effect on the stress of femur-prosthesis system. We assume that prosthesis, bone cement and femur are linear elas...

Histomorphometric analyses of the mandible and femur were performed in senescence-accelerated mice (SAM) using SAMP6 as a senile osteoporosis (OP) model, SAMP8 as a temporomandibular joint osteoarthritis (TMJOA) model, and SAMR1 as control. Thirty-six male mice at 2 or 4 months of age (6 for each strain and age) were used. The cortical thickness index (CTI), bone area (B.Ar/T.Ar), trabecular wi...

The prevalence of bone fractures increases markedly with age, which is correlated to osteoporosis, low bone mass and structural deterioration of trabecular bone. Infiltration of bone cement into vertebral bodies (vertebroplasty) has been shown to substantially increase the strength and stiffness of mechanically compromised trabecular bone. It was expected that a similar benefit might be realize...

Background: Osteoporosis is the most common metabolic disease of the bone in the world, and has hit about 200 million people around the world and it increases the risk of fractures. More than 5 million osteoporotic fractures occur annually in the world. Bone mineral density is the standard method of diagnosis of this disease. In this method, proximal of femur (neck) and lumbar vertebra bones (L...

BACKGROUND Infected nonunion of tibia and femur are common in clinical practice, however, the treatment of these diseases has still been a challenge for orthopaedic surgeons. Ilizarov methods can eradicate infection, compensate bone defects and promote the bone union through progressive bone histogenesis. The objective of this systematic review was to review current available studies reporting ...

Analysis of bone strength in radiographic images is an important component of estimation of bone quality in diseases such as osteoporosis. Conventional radiographic femur bone images are used to analyze its architecture using bi-dimensional empirical mode decomposition method. Surface interpolation of local maxima and minima points of an image is a crucial part of bi-dimensional empirical mode ...

BACKGROUND Quantitative computed tomography (QCT) imaging is the basis for multiple assessments of bone quality in the proximal femur, including volumetric bone mineral density (vBMD), tissue volume, estimation of bone strength using finite element modeling (FEM), cortical bone thickness, and computational-anatomy-based morphometry assessments. METHODS Here, we present an automatic framework ...

In this paper, a mathematical model is developed to simulate three-dimensional femur bone, taking into account the stress distribution and total displacement during horizontal walking. The principles of continuum mechanics, the field equations governing the displacement and stress fields in the femur bone including the stress equilibrium equations are used in the model. Realistic domain is crea...