نتایج جستجو برای: fed rat

تعداد نتایج: 355137  

Journal: :middle east journal of digestive diseases 0
hadi emamat maryam noori forough foroughi marjan rismanchi hassan eini–zinab azita hekmatdoost

background: there is no convenient cheap pragmatic experimental model for nonalcoholic fatty liver disease (nafld)/nonalcoholic steatohepatitis (nash). we aimed to create a pragmatic model of nafld/nash. methods: sprague-dawley rats were fed a high-fat, high sugar homemade diet ad libitum for seven weeks. the high-fat, high sugar diet included 59% of energy derived from fat, 30% from carbohydra...

Journal: :iranian journal of blood and cancer 0
somaye kalanaky alireza farsinejad saeede fakharzade mohammad ali karbasian morteza keshavarz azim mehrvar

abstract background: iron overload is a clinical consequence of repeated blood transfusions and causes significant organ damage, morbidity, and mortality in the absence of proper treatment. the primary targets of iron chelators used for treating transfusional iron overload are the prevention of iron ingress into tissues and its intracellular scavenging. the present study was aimed at elucidatin...

Journal: :Molecules 2015
Hyang Yeon Kim Mee Youn Lee Hye Min Park Yoo Kyoung Park Jong Cheol Shon Kwang-Hyeon Liu Choong Hwan Lee

In this study, we investigated the clinical changes induced by a high fat diet (HFD) and caffeine consumption in a rat model. The mean body weight of the HFD with caffeine (HFDC)-fed rat was decreased compared to that of the HFD-fed rat without caffeine. The levels of cholesterol, triglycerides (TGs), and free fatty acid, as well as the size of adipose tissue altered by HFD, were improved by ca...

Journal: :Journal of medical and dental sciences 2003
Daisuke Horie Mariko Takahashi Kazuhiro Aoki Keiichi Ohya

The pharmacological actions of bisphosphonates are due to the inhibitory effects on bone resorption, but little is known about the bisphosphonate action on bone formation. The purpose of this study is to elucidate the actions of bisphosphonates, clodronate, on bone formation in the experimental in vivo and in vitro rat models. The bone mineral density (BMD) was decreased in the rats fed a low-c...

Journal: :Annals of clinical and laboratory science 2002
Parimal Chowdhury Michael Soulsby

This study tested whether or not simulated weightlessness by tail-suspension increases the levels of lipid peroxidation products in rat brain. The brain tissues of rats on a soybean diet were also assayed for lipid peroxidation products to evaluate the possible role of soy-protein as a dietary anti-oxidant. Male Sprague-Dawley rats were used. Group 1 rats were fed standard Purina rat chow ad li...

Journal: :Journal of lipid research 1985
M Rasmussen R Blomhoff P Helgerud L A Solberg T Berg K R Norum

Chronic ethanol consumption reduces the liver retinoid store in man and rat. We have studied the effect of ethanol on some aspects of retinoid metabolism in parenchymal and nonparenchymal liver cells. Rats fed 36% of total energy intake as ethanol for 5-6 weeks had the liver retinoid concentration reduced to about one-third, as compared to pair-fed controls. The reduction in liver retinoid affe...

Journal: :Journal of lipid research 1981
D F Liau S A Hashim R N Pierson S F Ryan

Quantities and qualities of lipids in lung lavage and lavaged lung tissue were studied in ethanol-fed male Sprague-Dawley rats. Experimental rats received 36% of daily energy as ethanol for 7 weeks and each control rat, receiving an isocaloric amount of sucrose, was pair-fed with an experimental rat. Body weight gain and lung protein content in these two groups were similar. The mean lung dry w...

Journal: :Journal of nutritional science and vitaminology 2004
Akira Hirao Masao Yamasaki Hitomi Chujo Nami Koyanagi Hiroaki Kanouchi Shin Yasuda Aya Matsuo Eri Nishida Tatsuya Rikimaru Eiji Tsujita Mitsuo Shimada Yoshihiko Maehara Hirofumi Tachibana Koji Yamada

We examined the effect of dietary conjugated linoleic acid (CLA) on liver regeneration after a partial hepatectomy (PH) in Sprague-Dawley rats. PH was performed on rats fed a 0 or 1 wt.% CLA diet for 3 wk. Average liver weight in the CLA fed rat population was heavier than the control rat population at the time of PH and 1-d after PH. Conversely. CLA fed rats' liver weight was significantly low...

Journal: :Asia Pacific journal of clinical nutrition 2007
Ling Wang Ruo-Jun Xu

This study aimed to investigate the effects of perinatal protein malnutrition on brain derived-neurotrophic factor (BDNF) concentration in brain tissue and spatial learning and memory performance in young rats. Nine pregnant Wistar rats were assigned into three groups. Rats in one group were fed with a control diet containing 20% protein. Rats in remaining two groups were fed with a diet contai...

2003
ELIZABETH A. MURPHY R. C. ARCHIBALD R. E. CORNISH

Various observations necessarily made on vitamin E concentrates in connection with work on purification of vitamins (l), while outside the scope of that paper, disclosed many pitfalls which the experimenter may avoid with the information here presented. If certain simple precautions are not taken during extraction and saponification of the wheat germ oil, losses of over 90 per cent of its vitam...

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