background: the present study was formulated in order to determine pol­ymorphism of dihydropteroate synthetase gene (dhps) of plasmodium vivax (p . vivax ) in hormozgan province, southern iran and mutations at codons 382, 383, 512, 553, and 585 associated with resistance of p. vivax to sulfadoxine. method : one-hundred eighteen isolates of p. vivax were prepared within 2007-2008 to determine di...

BACKGROUND Existing school health programmes in Uganda target children above five years for de-worming, oral hygiene and frequent vaccination of girls of reproductive age. OBJECTIVE To assess primary school children's perspectives on common diseases they experience and medicines used in order to suggest reforms for school healthcare programmes and priority setting. METHODS Rapid appraisal a...

Elsie Nakirya, 66, heard her granddaughter Paula Nakafu, 6, moan uncharacteristically in her sleep. A quick check with her palm on the child’s forehead “confirmed” a high temperature. “I sponged her off until morning, then went to a drug store and bought chloroquine syrup and a tablet of Fansidar [sulphadoxine–pyremethamine (SP)],” said Nakirya, a resident of Makerere West, a suburb of Kampala....

background: the capacity of human hbaa erythrocytes of non-malarious blood to withstand osmotic stress in the presence of five antimalarial drugs, chloroquine phosphate, quinine, fansidartm, coartemtm and halfantm was studied in vitro. materials and methods: aqueous solutions of four increasing concentrations of the drugs used in this investigation were in the order: 0.2%, 0.4%, 0.6% and 0.8% (...

Chloroquine (CQ) and fansidar (sulphadoxine-pyrimethamine, SP) were widely used for treatment of Plasmodium falciparum for several decades in Malaysia prior to the introduction of Artemisinin-based Combination Therapy (ACT) in 2008. Our previous study in Kalabakan, located in south-east coast of Sabah showed a high prevalence of resistance to CQ and SP, suggesting the use of the treatment may n...

.. Malaria is one of the devastating diseases worldwide. More than 3 billion people live under the threat of malaria in endemic countries and kills more than one million each year. Malaria leads to multiple hematological (thrombocytopenia) and other abnormalities like renal system, nervous system with increased morbidity and mortality. Aim: The present study was conducted to determine the preva...

The incidence density of infection and disease caused by Plasmodium falciparum in children aged six to 24 months living in the holoendemic Sahel of northern Ghana was measured during the wet and dry seasons of 1996 and 1997. At the beginning of each season, a cohort composed of 259 and 277 randomly selected children received supervised curative therapy with quinine and Fansidar and primaquine f...

In Tanzania, the coverage of four or more antenatal care (ANC 4) visits among pregnant women has declined over time. We conducted an exploratory analysis to identify factors associated with utilization of ANC 4 and ANC 4 decline among pregnant women over time. We used data from 8035 women who delivered within two years preceding Tanzania Demographic and Health Surveys conducted in 1999, 2004/05...

UNLABELLED Pharmacies are managed by a variety of dispensers in terms of qualification, knowledge and experience in Pakistan. OBJECTIVE The study aimed to document the state of knowledge, experience and qualification of dispensers working at community pharmacies in Pakistan. METHODS A comparative cross sectional study was conducted at a randomly selected sample of 371 pharmacies in the thre...