II Declaration I declare that the work described in this dissertation is, except where otherwise stated, entirely my own work and has not been submitted as an exercise for a degree at this or any other university. Abstract The exponential growth of the Internet and the increasing demands put upon Web servers has created the need for a scalable clustered Web servers. In this paper we attempt to ...

turnip mosaic virus (tumv) is amember of the potyvirus genus within the potyviridae family and is one the most important viruses infecting brassicaceae plants. in april 2012, suspicious symptoms of a viral disease such as mosaic, stunting and malformation were observed on herschfeldia incana. the collected samples were tested using reverse transcription-polymerase chain reaction (rt-pcr) with s...

In this paper we introduce a family of planar, modular and self-similar graphs which have small-world and scale-free properties. The main parameters of this family are comparable to those of networks associated with complex systems, and therefore the graphs are of interest as mathematical models for these systems. As the clustering coefficient of the graphs is zero, this family is an explicit c...

On the Bacillus subtilis chromosome there are five examples of genes encoding two-component systems with response regulators of the OmpR family adjacent to genes encoding sub-family 9 ABC transport systems. Three of these (yts, yvc, yxd) are very similar in gene organization and in sequence. We demonstrate that the TCS and ABC transporter genes do not belong to the same transcriptional unit. Th...

We performed a bioinformatical analysis of protein export elements (PEXEL) in the putative proteome of the malaria parasite Plasmodium falciparum. A protein family-specific conservation of physicochemical residue profiles was found for PEXEL-flanking sequence regions. We demonstrate that the family members can be clustered based on the flanking regions only and display characteristic hydrophobi...

Thirteen and 10 sequences of the Alu family of repeated DNA elements found within the human thymidine kinase and beta-tubulin genes, respectively, were compared. These genes have approximately five times the expected density of Alu family members. The consensus sequence that could be drawn from these 23 Alu family members would differ slightly from others drawn from random Alu family sequences ...

Motivated by the cooperative breeding hypothesis, we investigate the effect of having kin on the mortality of reproductive women based on family reconstitutions for the Krummhörn region (East Frisia, Germany, 1720-1874). We rely on a combination of Cox clustered hazard models and hazard models stratified at the family level. In order to study behavior-related effects, we run a series of models ...

We present a family of networks, expanded deterministic Apollonian networks, which are a generalization of the Apollonian networks and are simultaneously scale-free, small-world, and highly clustered. We introduce a labeling of their vertices that allows to determine a shortest path routing between any two vertices of the network based only on the labels.

The study of isolated, inbred populations is a promising approach for the identification of disease susceptibility genes. One of the main challenges for geneticists and epidemiologist is to deal with the very complex genealogies of such populations. We present ongoing research on using a visual analytics based approach for the identification of family clustered diseases, risk factors and herita...