نتایج جستجو برای: familial dysautonomia

تعداد نتایج: 56514  

Journal: :Journal of neurology, neurosurgery, and psychiatry 1964
W J BROWN J A BEAUCHEMIN L M LINDE

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2015
Huisha Xu Zhijie Lin Fengzhi Li Wentao Diao Chunming Dong Hao Zhou Xingqiao Xie Zheng Wang Yuequan Shen Jiafu Long

The evolutionarily conserved Elongator complex, which is composed of six subunits elongator protein 1 (Elp1 to -6), plays vital roles in gene regulation. The molecular hallmark of familial dysautonomia (FD) is the splicing mutation of Elp1 [also known as IκB kinase complex-associated protein (IKAP)] in the nervous system that is believed to be the primary cause of the devastating symptoms of th...

Journal: :Journal of Neuropathology & Experimental Neurology 2017

Journal: :Canadian Anaesthetists’ Society Journal 1971

Journal: :JPMA. The Journal of the Pakistan Medical Association 1997
M Atiq K Aziz

Familial cardiac conduction disorder of a progressive nature has been reported in adult and paediatric patients. An underlying cardiomyopathy was found in most of these patients, either of hypertrophic, restrictive or dilated variety. Systemic diseases like juvenile rheumatoid arthritis and other collagen disorders and familial dysautonomia infrequently have associated conduction abnormalities....

Journal: :Evidence-based Complementary and Alternative Medicine : eCAM 2009
Derrick Lonsdale

Dysautonomia refers to a disease where the autonomic nervous system is dysfunctional. This may be a central control mechanism, as in genetically determined familial dysautonomia (Riley-Day Syndrome), or peripherally in the distribution of the sympathetic and parasympathetic systems. There are multiple reports of a number of different diseases associated with dysautonomia. The etiology of this a...

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