The antibody-based delivery of IL2 to extracellular targets expressed in the easily accessible tumor-associated vasculature has shown potent antileukemic activity in xenograft and immunocompetent murine models of acute myelogenous leukemia (AML), especially in combination with cytarabine. Here, we report our experience with 4 patients with relapsed AML after allogeneic hematopoietic stem cell t...

In this paper we show that the polynomial x − 5x +12x − 28x +72x − 132x + 116x − 74x + 90x − 28x − 12x + 24x − 12x − 4x − 3x − 1 ∈ Q[x] has Galois group SL2(F16), filling in a gap in the tables of Jürgen Klüners and Gunther Malle (see [12]). The computation of this polynomial uses modular forms and their Galois representations.

Labor Demand Effects of Rising Electricity Prices: Evidence for Germany Germany plays a pioneering role in replacing conventional power plants with renewable energy sources. While this is beneficial with respect to environmental quality, the energy turnaround implies increasing electricity prices for private households and firms. The extent to which this is associated with negative impacts on e...

Vaux et al. (D. J. T. Vaux, A. Helenius, and I. Mellman, Nature (London) 336:36-42, 1988) recently reported the production of network antibodies that were suggested to have reconstructed a specific interaction between the nucleocapsid of Semliki Forest virus and the cytoplasmic tail of the viral E2 spike protein. The F13 anti-idiotype antibody, which was raised against anti-E2 tail antibodies, ...

It has been shown previously that the fusion glycoprotein of human respiratory syncytial virus (RSV-F) interacts with cellular heparan sulfate. Synthetic overlapping peptides derived from the F-protein sequence of RSV subtype A (strain A2) were tested for their ability to bind heparin using heparin-agarose affinity chromatography (HAAC). This evaluation identified 15 peptides representing eight...

Larva Black Soldier Fly (BSF) dikenal sebagai agen pendegradasi bahan organik. Kemampuan hidup di lingkungan yang kaya mikorba seperti limbah organik tentu menuntut sistem kekebalan tubuh kuat dari larva BSF. BSF (Hermetia illucens) berpotensi sumber agensia hayati karena akan mikroorganisme. Penelitian ini bertujuan mengisolasi dan seleksi bakteri bersifat antagonis terhadap Rhizoctonia solani...

Article history: Received 23 October 2010 Received in revised form 4 January 2012 Accepted 6 January 2012 Available online 14 January 2012 JEL classification: F10 F12 F14 F16 L22 J24