A one-pot synthesis of micellar spherical nucleic acid (SNA) nanostructures using Pluronic F127 as a thermoresponsive template is reported. These novel constructs are synthesized in a chemically straightforward process that involves intercalation of the lipid tails of DNA amphiphiles (CpG motifs for TLR-9 stimulation) into the hydrophobic regions of Pluronic F127 micelles, followed by chemical ...

We report the synthesis of hydroxyapatite nanoparticles (HANPs) by the coprecipitation method using calcium D-gluconate and potassium hydrogen phosphate as the sources of calcium and phosphate ions, respectively, and the triblock copolymer F127 as a stabilizer. The HANPs were characterized using scanning electron microscopy, x-ray diffraction, and nitrogen adsorption/desorption isotherms. Remov...

In this study, we report on CdS/ZnS nanocrystals as a luminescence probe for bioimaging applications. CdS nanocrystals capped with a ZnS shell had enhanced luminescence intensity, stronger stability and exhibited a longer lifetime compared to uncapped CdS. The CdS/ZnS nanocrystals were stabilized in Pluronic F127 block copolymer micelles, offering an optically and colloidally stable contrast ag...

By using cyclodextrin (α-CD) self-assembly into a hydrogel with the triblock copolymer Pluronic F127, nanomicrocrystalline cellulose was introduced into a gel system to form a composite CNC-β-CD/α-CD/Pluronic F127 hydrogel (CCH). CCH was modified further by grafting acrylic acid to form a novel acrylated composite hydrogel (ACH). The swelling degree of ACH was 156 g/g. Adsorption isotherms show...

Non-specific protein adsorption is detrimental to the performance of many biomedical devices. Polystyrene is a commonly used material in devices and thin films. Simple reliable surface modification of polystyrene to render it protein resistant is desired in particular for device fabrication and orthogonal functionalisation schemes. This report details modifications carried out on a polystyrene ...

Influence of synthesis temperature on morphology of SBA-16 mesoporous materials with a three-dimensional pore system, Abstract Spherical particles of mesoporous silica SBA-16 with cubic Im3m structure were synthesized at low pH using Pluronic F127 as template and TEOS as silica source. The diameter of the spherical particles can be controlled in the range of 0.5 – 8 µm by varying synthesis temp...

Aqueous single-walled carbon nanotube dispersions are often made using polymers from the Pluronic family of amphiphilic block copolymers, however relatively few studies have been made using small-angle neutron scattering techniques to discover the mechanism by which they act. SANS results reported here show that a relatively simple core-shell cylinder model can be used to fit data successfully ...

To determine Zidovudine (AZT) and Lamivudine (3TC) at the same time based on PAMAM dendrimer modified with Pluronic F127, application as anti-HIV drug control. A fast, accurate HPLC-PDA determination of AZT 3TC high reliability selectivity has been developed validated according to ICH (International Conference Harmonisation Technical Requirements for Registration Pharmaceuticals Human Use) guid...

Herein, we explore the idea of self-assembly of nearly monodisperse nanoparticles as uniform building blocks to design highly crystalline mesoporous TiO(2) nanoparticles, through evaporation-induced self-assembly (EISA) and hydrothermal methods by using non-ionic Pluronic F127 and anionic surfactant SDS, respectively as structure directing agents. The small- and wide-angle powder X-ray diffract...

Abstract: Background: Colorectal cancer (CRC) has grown to be the world’s fourth-biggest cause of cancer-related mortality. It is critical identify more effective treatment options for it. Objectives: Doxorubicin a potent antineoplastic agent widely used but severe adverse effects. Therefore, our objective use cubosome as an efficient drug delivery system reduce off-target effects and increase ...