background: although opioids suppressive effects on immune system function have been reported, this study demonstrates inflammatory reactions, such as production of pro-inflammatory cytokines and suppression of anti-inflammatory cytokines, are the main causes at organ’s allotransplantation rejection in chronic morphine-treated recipients. methods: 28 rats were categorized in 4groups through int...

in a r etrospective s t udy on the c ancer o f the gal l bladder, done in iran, it s e ems tha t it compr ises 0 . 36% o f a ll the malignant tumors . 1 .7 5% of the patients were fema les and the maximum incidenc e wa s in t he s i x th decade of l i f e. it was interesting t o note that the age ratio bet ween t he males and f ema le s reverses with t he advance o f a ge, s o at the 7th and 8t...

To develop a safe and efficient Aβ vaccine for Alzheimer's disease, we constructed a plasmid DNA vaccine encoding ten repeats of Aβ3-10 and three copies of C3d-p28 as a molecular adjuvant and administered it intramuscularly in 12-month-old female Tg-APPswe/PSEN1dE9 mice. Therapeutic immunization with p(Aβ3-10)10-C3d-p28.3 stimulated a Th2 immune response that elicited therapeutic levels of anti...

g l o b a l c o m p e t i t i v e n e s s h a s r e c e n t l y b e c o m e a b i g c h a l l e n g e f o r m a n y c o m p a n i e s a r o u n d t h e w o r l d, w h i c h a r e f o r c e d t o s e e k l o w e r c o s t s a n d h i g h e r q u a l i t y f o r w h a t t h e y p r o d u c e. t h e p r o s p e r i t y o f m a n u f a c t u r i n g f i r m s d e p e n d s o n s e l e c t i n g a n...

background: activation of inflammatory cells can cause more chemicals induced-hepatotoxicity. aflatoxin b1 (afb1) is a fungal toxin that induces acute hepatotoxicity in humans and animals. this study was conducted to examine the effect of co-exposure lps and various aflatoxin b1 doses on the damage hepatic parameters in isolated perfused rat liver. methods: thirty-two male wistar rats (250-300g...

Plasma samples from 44 patients with systemic lupus erythematosus (SLE) and 43 with rheumatoid arthritis (RA) were assayed for C3d, a breakdown product of the third component of complement (C3), which was also measured in parallel. Levels of C3d varied in direct proportion with disease activity in RA, whereas C3 showed little change. Although C3d values also increased with worsening clinical co...

in this paper, we define and study the notion of the real-valued functions on a frame $l$. we show that $f(l) $, consisting of all frame homomorphisms from the power set of $mathbb{r}$ to a frame $ l$, is an $f$-ring, as a generalization of all functions from a set $x$ into $mathbb r$. also, we show that $f(l) $ is isomorphic to a sub-$f$-ring of $mathcal{r}(l)$, the ring of real-valued continu...

introduction: quality of life play a considerable role in individual and social health. low back pain is the most common musculoskeletal disorders and cause negative impacts on various aspects of life. the aim of study was to compare the quality of life of students with and without low back pain.  materials and methods: this was across-sectional study performed among students at the faculty of ...

background: malassezia furfur is alipophilic yeast that causes skin disease. objective: to evaluate the level of il-10, ifn-γ and il-12p70 in co-incubation of m. furfur grown on different forms of natural oils with pbmcs of healthy individuals. methods: pbmcs were obtained from blood samples of normal volunteers. m. furfur was cultured in different culture media containing almond oil, fish oil,...