Self inflicted injury to the eyes including self-enucleation is a rare phenomenon. The authors describe a case of bilateral self-enucleation in a patient with paranoid schizophrenia. A review of literature shows that self-enucleation is correlated with moral, religious and psychodynamic paradigms and various unconscious mechanisms have been proposed to explain this unusual behaviour.

AIMS To determine the epithelial proliferative capacity of organ cultured limbal tissue and correlate this with various donor and eye banking factors. METHODS 24 corneoscleral limbal (CSL) rims left over from penetrating keratoplasty were split in half and set up as in vitro explant cultures. Corneal epithelial proliferative potential (CEPP) was assessed by the number of "cycles" of growth ac...

PURPOSE To demonstrate the ability of multiphoton microscopy to obtain full three-dimensional high-resolution images of the intact mouse eye anterior chamber without need for enucleation. METHODS A custom multiphoton microscope was constructed and optimized for deep tissue imaging. Simultaneous two-photon autofluorescence (2PAF) and second harmonic generation (SHG) imaging were performed. A m...

2 cases of diffuse malignant ring melanoma of the anterior uvea are presented. A correct clinical diagnosis led to enucleation in case 1, while in case 2, the eye was enucleated 2 years after anti-glaucomatous surgery.

Microphthalmos with orbital cyst is a rare congenital abnormality of fetal fissure closure leading to small eyeball associated an cyst. In this case series, we describe six such cases and discuss the clinical features, differential diagnosis, diagnostic modalities, management in accordance existing literature. Out cases, four were male two females. All presented swelling lower eyelid involved e...

Abstract Eales’ disease is a retinal vasculitis characterized by inflammation, ischemia, and neovascularization. Exact pathogenesis of this yet to be found out. We present 29-year-old male, diagnosed with in both eyes persistent intraocular inflammation. Enucleation the pthisical right eye was subjected for histopathological examination immunohistochemistry molecular biologic study mycobacteria...

Explosions, man-made and accidental, continue to require improved emergency medical responses. In the 1917 Halifax Explosion, an inordinate number of penetrating eye injuries occurred. A review of their treatment provides insight into a traumatic event with unique ophthalmological importance. Archived personal and government documents relating to the Halifax Explosion were reviewed at the Publi...

PURPOSE To evaluate the hypothesis that the expression of the calcium-binding protein parvalbumin (PV) in a subpopulation of gamma-aminobutyric acid (GABA)ergic neurons is an appropriate molecular marker for the effect on ocular dominance plasticity of monocular deprivation during the postnatal sensitive period. METHODS Long-Evans rats underwent monocular enucleation immediately before eye op...