OBJECTIVE To identify risk factors for extubation failure and reintubation in newborn infants subjected to mechanical ventilation and to establish whether ventilation parameters and blood gas analysis behave as predictors of those outcomes. METHODS Prospective study conducted at a neonatal intensive care unit from May to November 2011. A total of 176 infants of both genders subjected to mecha...

OBJECTIVES To describe the epidemiology of extubation failure and identify risk factors for its occurrence in a multicenter population of neonates undergoing surgery for congenital heart disease. STUDY DESIGN We conducted a prospective observational study of neonates ≤30 days of age who underwent cardiac surgery at 7 centers within the US in 2015. Extubation failure was defined as reintubatio...

Background Self-extubation is a problem in pediatric intensive care unit (PICU) and can be harmful for children. Level of sedation is a determining factor for self-extubation. The aim of this study was to compare thr rate of self-extubation and duration of ventilation following different sedative modalities. Materials and Methods This prospective and randomized study was done in Mofid Children ...

Methods In this retrospective case note study we looked at the outcome of each extubation between 1st October 2013 and 30th September 2014. We included all patients >18 years of age invasively ventilated for >48 hours. We excluded patients proceeding directly to tracheostomy or extubated for withdrawal of care. Failed extubation was defined as the need for reintubation within 5 days of planned ...

In neurologically injured patients, predictors for extubation success are not well defined. Abnormal breathing patterns may result from the underlying neurological injury. We present three patients with abnormal breathing patterns highlighting failure of successful extubation as a result of these neurologically driven breathing patterns. Recognizing abnormal breathing patterns may be predictive...

introduction: response to tracheal tube during emergence of general anesthesia is a main concern. we aimed to compare the effect of remifentanil and lidocaine on response to tracheal tube during emergence of general anesthesia. materials and methods: in this randomized clinical trial, we enrolled 80 consecutive patients with american society of anesthesiology (asa) physical status i–ii, who und...

We conducted this study to find out the incidence of extubation failure (EF) in ventilated neonates and associated clinical risk factors. Eighty two ventilated neonates were followed up to 48 hours post extubation to look for EF. Twenty two babies (26.8%) had EF. The common risk factors for EF were presence of patent ductus arteriosus, post-extubation lung collapse and acquired pneumonia. The d...

OBJECTIVE To report successful cases of extubation from invasive mechanical ventilation at our institution using pulmonary rehabilitation consisting of noninvasive ventilation (NIV) in neuromuscular patients with experience of reintubation. METHODS Patients who experienced extubation failure via the conventional weaning strategy but afterwards had extubation success via NIV were studied retro...