For opportunistic pathogens such as Pseudomonas aeruginosa, the mucosal barrier represents a formidable challenge. Infections develop only in patients with altered epithelial barriers. Here, we showed that P. aeruginosa interacts with a polarized epithelium, adhering almost exclusively at sites of multi-cellular junctions. In these sites, numerous bacteria attach to an extruded apoptotic cell o...

To evaluate the amount of apically extruded debris, percentage of foraminal enlargement and apical foramen (AF) deformation that occurred during root canal preparation with different reciprocation systems: Reciproc, WaveOne (M-Wire), and ProDesign R (Shape Memory Technology Wire) at two different working lengths (WLs): 0.0 and 1.0 mm beyond the AF. The AF of 120 root canals in 60 mesial roots o...

The aim of this study was to evaluate the efficacy of ProTaper and K3 in the removal of gutta-percha during root canal retreatment in comparison with hand Hedstrom files. Time of gutta-percha removal and amount of apically extruded debris were also evaluated. Sixty extracted single-rooted anterior teeth and premolars were instrumented and obturated with laterally condensed gutta-percha techniqu...

Aims: Assess the quantity of apical extruded debris after instrumentation with ProTaper universal files, K3 and Wave One reciprocating file. Materials Methods: Thirty lower premolars were used in this study. Teeth randomly divided into 3 groups each one contained 10 samples as follow: Group1- prepared files. Group2- Group3- Debris that was apically during canals preparation collected centrifuge...

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