7,8-dihydro-8-oxoguanine (oxoG), the predominant lesion formed following oxidative damage of DNA by reactive oxygen species, is processed differently by replicative and bypass polymerases. Our kinetic primer extension studies demonstrate that the bypass polymerase Dpo4 preferentially inserts C opposite oxoG, and also preferentially extends from the oxoG*C base pair, thus achieving error-free by...

Submitted for the MAR10 Meeting of The American Physical Society Extension of the Source-Sink Potential (SSP) approach for multichannel conductance calculations PHILIPPE ROCHELEAU, MATTHIAS ERNZERHOF, Universite de Montreal — In molecular electronics, molecules are connected to macroscopic contacts and the current passing through is studied as a function of the applied voltage. We focus on mode...

We report a broadband-gain superluminescent diode (SLD) based on self-assembled InAs quantum dots (QDs) for application in a high-resolution optical coherence tomography (OCT) light source. Four InAs QD layers, with sequentially shifted emission wavelengths achieved by varying the thickness of the In0.2Ga0.8As strain-reducing capping layers, were embedded in a conventional p-n heterojunction co...

BACKGROUND Postpartum parental mental health problems pose a serious risk for child development and often remain undetected in postpartum primary care. Within the framework of the German Midwifes Prevention Study, the aim of this study was to investigate the presence of postpartum emotional distress in mothers and fathers, and the detection of distressed parents by midwives in a primary care se...

The asymmetric unit of the title compound,  Contains two independent molecules. The Cu atoms are four coordinated in distorted tetrahedral configuration by two atoms from 5,5`-dimethyl-2,2`- bipyridine and two terminal atoms. In the Cuystal structure, inter molecular hydrogen bonds link the molecules. The are  contacts between the methyl groups and the pyridine and five member rings containing ...

the purpose of this study was to assess the process of extension program development in iranian agricultural extension system (iaes). the research instrument was a structural questionnaire with close-ended questions which its validity and reliability was confirmed by using expert panel and cranach’s alpha test, respectively. the target population of this research included all extension managers...

although mental health program has been adopted as one of the components of the primary health care program in iran since 1989 its cost effectiveness has not yet been evaluated in any form. the purpose of the present study was to evaluate the cost-effectiveness of mental health program regarding the treatment of epileptic patients in the kurdestan province.in order to achieve the above goal in ...

Circuit Breakers (CBs) are critical components in power system for reliability and protection. To assure their accurate performance, a comprehensive condition assessment is of an imminent importance. Based on dynamic resistance measurement (DRM), this paper discusses a simple yet effective fuzzy approach for evaluating CB’s electrical contacts condition. According to 300 test results obta...

Introduction: Rapid public health response is important in controlling the transmission of coronavirus disease 2019 (COVID-19). In this study, we described the public health response received by the Ministry of Health of Malaysia in managing the first local transmission cluster of COVID-19 related to mass-gathering and inter-state traveling to celebrate a festival. <stron...

the purpose of this study was to determine the effect of farmer field school (ffs) approach on adoption of biological control by rice farmers. the research population consisted of 72 farmers who had participated in ffs and 346 who had not participated in ffs, selected through randomized sampling method. the methodological approach of the study was twofold: descriptive-correlative and causal-com...