In a healthy human, deep inspirations produce bronchodilation of contracted airways, which probably occurs due to the transient distension of the airway smooth muscle (ASM). We hypothesised that deep expiratory manoeuvres also produce bronchodilation due to transient airway wall and ASM compression. We used porcine bronchial segments to assess the effects of deep inspirations, and maximal and p...

[Purpose] The aim of this investigation was to determine the effects of 4 weeks of fast expiration exercises performed without pressure on respiratory muscle strength. [Subjects and Methods] Respiratory muscle strength of the training group that performed fast expiration exercises (n=12) was compared with that of a control group that performed no exercises (n=12). The fast expiration exercises ...

To test the hypothesis that a respiratory cycle influences pain processing, we conducted an experimental pain study in 10 healthy volunteers. Intraepidermal electrical stimulation (IES) with a concentric bipolar needle electrode was applied to the hand dorsum at pain perceptual threshold or four times the perceptual threshold to produce first pain during expiration or inspiration either of whic...

To determine whether the canine right ventricle (RV) can develop a negative diastolic pressure indicative of suction, RV pressure was measured in 15 dogs, with catheter-tip micromanometers. Six dogs were studied only with the chest closed. In these dogs, intrapleural pressure was measured medially (near the heart) in four and laterally in two. In nine dogs, RV pressure was evaluated with the ch...

The goal of the present study was to evaluate the relative plausibility of the models of the central respiratory pattern generator (CRPG) proposed in our previous paper. To test the models, we compared changes in generated patterns with the experimentally observed alterations of the respiratory pattern induced by various stimuli applied to superior laryngeal (SLN), vagus and carotid sinus (CS) ...

Critical Care Medicine www.ccmjournal.org e65 Objective: Cyclic recruitment and derecruitment of atelectasis can occur during mechanical ventilation, especially in injured lungs. Experimentally, cyclic recruitment and derecruitment can be quantified by respiration-dependent changes in Pao2 (ΔPao2), reflecting the varying intrapulmonary shunt fraction within the respiratory cycle. This study inv...

OBJECTIVE To evaluate how changes in lung volume affect volumetric measurements of lung nodules using a multi-detector row CT. MATERIALS AND METHODS Ten subjects with asthma or chronic bronchitis who had one or more lung nodules were included. For each subject, two sets of CT images were obtained at inspiration and at expiration. A total of 33 nodules (23 nodules > or =3 mm) were identified a...

We propose an algorithm to determine stable connected dominating sets (CDS), based on the predicted link expiration time (LET), for mobile ad hoc networks (MANETs). The proposed LETbased CDS algorithm is the first such algorithm that constructs a CDS based on edge weights represented by predicted link expiration time, rather the traditional approach of using node weights like the wellknown maxi...

background chronic obstructive pulmonary disease (copd) is a devastating disease.while there is no cure for copd and the lung damage associated with this disease cannot be reversed, it is still very important to diagnose it as early as possible. objectives in this paper, we propose a novel method based on the measurement of air trapping in the lungs from ct images to detect copd and to evaluate...