نتایج جستجو برای: exotoxins

تعداد نتایج: 1304  

2018
Adam J Pelzek Bo Shopsin Emily E Radke Kayan Tam Beatrix M Ueberheide David Fenyö Stuart M Brown Qianhao Li Ada Rubin Yi Fulmer William K Chiang David N Hernandez Hanane El Bannoudi William E Sause Alexis Sommerfield Isaac P Thomsen Andy O Miller Victor J Torres Gregg J Silverman

Staphylococcus aureus is a Gram-positive opportunistic pathogen that causes superficial and invasive infections in the hospital and community. High mortality from infection emphasizes the need for improved methods for prevention and treatment. Although S. aureus possesses an arsenal of virulence factors that contribute to evasion of host defenses, few studies have examined long-term humoral and...

Journal: :Journal of bacteriology 2011
Shantanu Bhatt Akwasi Anyanful Daniel Kalman

Enteropathogenic Escherichia coli(EPEC) requires the tnaA-encoded enzyme tryptophanase and its substrate tryptophan to synthesize diffusible exotoxins that kill the nematode Caenorhabditis elegans. Here, we demonstrate that the RNA-binding protein CsrA and the tryptophan permease TnaB coregulate tryptophanase activity, through mutually exclusive pathways, to stimulate toxin-mediated paralysis a...

2015
Mahendra Kumar Trivedi

Study background: Staphylococci are widespread in nature, mainly found on the skin and mucous membranes. Staphylococcus aureus (S. aureus) is the key organism for food poisoning due to massive production of heat stable exotoxins. The current study was attempted to investigate the effect of biofield treatment on antimicrobial susceptibility pattern and biochemical characteristics of S. aureus (A...

Journal: :Infection and immunity 1999
U Sibelius E C Schulz F Rose K Hattar T Jacobs S Weiss T Chakraborty W Seeger F Grimminger

Polymorphonuclear leukocytes (PMN) are essential for resolution of infections with Listeria monocytogenes. The present study investigated the role of the listerial exotoxins listeriolysin (LLO) and phosphatidylinositol-specific phospholipase C (PlcA) in human neutrophil activation. Different Listeria strains, mutated in individual virulence genes, as well as purified LLO were used. Coincubation...

Journal: :International archives of allergy and immunology 2014
Margarete Niebuhr Julia Mainardy Annice Heratizadeh Imke Satzger Thomas Werfel

BACKGROUND We have shown previously that T cells from atopic dermatitis (AD) patients produce more IL-22 upon staphylococcal exotoxin stimulation compared to psoriasis patients and healthy controls. The role of staphylococcal exotoxins on polarized memory T helper (Th)22 cells which are enriched in inflamed AD skin remains elusive. Our aim was to investigate IL-22 production in response to stap...

Journal: :Journal of clinical microbiology 2005
Ivana Dakić Dragana Vukovic Srdjan Stepanović Tomasz Hauschild Petr Jezek Petr Petrás Donald Morrison

Genes encoding staphylococcal enterotoxins (sea to see, seg, and seh), toxic shock syndrome toxin 1 (tst), and exfoliative toxins (eta and etb) were not detected in a large panel of 48 Staphylococcus sciuri group isolates tested. This strongly suggests that production of the staphylococcal exotoxins by these bacteria is highly unlikely.

Journal: :Journal of clinical microbiology 2011
Rama Chaudhry Nishant Verma Tej Bahadur Parul Chaudhary Pallavi Sharma Nidhi Sharma

Systemic infections caused by Clostridium sordellii are rare. They are usually reported in cases of skin and soft tissue infections and sometimes in cases of toxic shock syndrome involving exotoxins. We report here the first case of Clostridium sordellii infection associated with acute constrictive pericarditis and with pyopericardium and tamponade.

Journal: :Bangladesh Journal of Medical Science 2021

Background: This work describes etiological structure and statistics for causes of acute enteric infections salmonellosis in modern conditions.
 Method: It was analyzed the common epidemiologic signs indices (AEI), caused by opportunistic microorganisms (OMO), various viruses salmonella.
 Result: The research also shows integrative intoxication indicators causal groups endogenous whic...

Journal: :Critical Care 2001
Martin Llewelyn Jonathan Cohen

The production of superantigenic exotoxins by Gram positive bacteria underlies the pathology of toxic shock syndrome. Future treatment strategies for superantigen-mediated diseases are likely to be directed at blocking the three-way interaction between superantigen, T cell receptor and major histocompatibility class II molecule, which inititates an excessive and disordered inflammatory response...

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