Running title (max 54 characters including space): 25 Structure of the mobile B3 MBL: AIM-1 26 27

[This corrects the article on p. 532 in vol. 7, PMID: 29379773.].

Pseudomonas aeruginosa is an opportunistic pathogen which uses a number of strategies to cross epithelial and endothelial barriers at cell-cell junctions. In this review, we describe how the coordinated actions of P. aeruginosa's virulence factors trigger various molecular mechanisms to disarm the junctional gate responsible for tissue integrity.

Considerable improvements have been made in the fogging application of Rejex-it TP-40. Much has been learned about the type of fog generated by these machines and the resulting efficiency. Many foggers have been proven to deliver the product in the desired form, while others were only useful under special conditions, but no single piece of equipment is suitable for all situations. Generally, th...

We demonstrate that pancreatic cancer tissues express receptors for interleukin (IL)-4 in situ at high density. Using the approach of selective receptor targeting, we have tested the efficacy of a recombinant cytotoxin IL4-Pseudomonas exotoxin A, which is composed of a targeting moiety (IL-4) and a mutated form of Pseudomonas exotoxin. Our results demonstrate that this molecule exerts vigorous ...

CAMERO , C. M. & SMIT, MARIA, C. Relationship of Corynebacterium pseudotuberculosis protoplasmic toxins to the exotoxin. Onderstep oort]. vet. Res. (1970), 37 (2), 97-104. Corynebacterium pseudotttberculosis (Buchanan, 1911) protoplasm was separated into two tox ic fractions by means of gel chromatography. Toxin neutralization tests indicated that one of the fractions is probably identical to t...

The dicarbonyl compound methylglyoxal is a natural constituent of Manuka honey produced from Manuka flowers in New Zealand. It is known to possess both anticancer and antibacterial activity. Such observations prompted to investigate the ability of methylglyoxal as a potent drug against multidrug resistant Pseudomonas aeruginosa. A total of 12 test P. aeruginosa strains isolated from various hos...

Cepharanthine, a biscoclaurine alkaloid, causes an 8-fold enhancement of the cytotoxic effect of a conjugate of epidermal growth factor (EGF) coupled with Pseudomonas exotoxin in HeLa cells. Cepharanthine also potentiates the effect of Pseudomonas exotoxin. Cepharanthine does not affect the binding and uptake of 125I-EGF by HeLa cells, but it delays the release of radioactivity associated with ...