Members of four generations of a family had a defect of serum opsonization for yeast phagocytosis consistent with dominant inheritance. 2 were healthy, one had chronic osteomyelitis, and the fourth developed a fatal illness in infancy characterized by exfoliative dermatitis, diarrhoea, multiple bacterial infections, and failure to thrive, which resembled the two prevously reported cases with th...

Sir, Dapsone therapy can cause severe adverse reactions known as the sulphone or dapsone hypersensitivity syndrome (DS). The most common presenting symptom is a maculopapular or exfoliative rash confined to either the upper limbs or the forehead, but it can also be disseminated. The sequence of symptoms – dermatitis, lymphadenopathy notably along the posterior border of the sternomastoid muscle...

The course of infection in a 3-week-old premature newborn suffering from extensive dermatitis with flaccid blisters is described. Staphylococcus aureus was recovered from a local wound infection around a chest tube inserted to drain a postoperative chylothorax. The strain isolated tested positive for the eta gene for exfoliative toxin A, the causative agent of staphylococcal scalded-skin syndro...

Pemphigus foliaceus is an autoimmune disease having a chronic generalized course or may rarely present as an exfoliative dermatitis. Presence of occult HSV infection is involved in development of pemphigus and immunosuppressive therapy for pemphigus results in flare of typical or atypical herpetic lesions. We herein report of a case of a 48 year old male on immunosuppressive therapy for pemphig...

The exfoliative cytology of 14 diffuse mesothelioma (11 pleural and three peritoneal) is described. Malignant cells were identified in 10 patients; in eight malignant cells still retaining the characteristics of mesothelial cells were found. It is suggested that only if malignant cells of this type are recognized should the probable diagnosis of diffuse mesothelioma be made.