نتایج جستجو برای: ewings sarcoma
تعداد نتایج: 74268 فیلتر نتایج به سال:
Over the past three decades, the outcome of Ewing sarcoma family tumor (ESFT) patients who are nonmetastatic at presentation has improved considerably. The prognosis of patients with metastatic disease at the time of diagnosis and recurrence after therapy remains dismal. Drug-resistant disease at diagnosis or at relapse remains a major cause of mortality among patients diagnosed with ESFT. In o...
There is no consensus on the optimal method of local control in Ewing's sarcoma (ES) of the mobile spine. Recent reports have suggested that en bloc resection may improve local control and survival. The authors therefore performed a systematic review to answer the following questions: (1) What is the outcome of en bloc resection for ES of the mobile spine with respect to local control and disea...
Ewing's sarcoma family tumors (EFT) are characterized by specific chromosomal translocations, which lead to EWS/ETS transcription factors. Elucidation of EWS/ETS target gene networks within the context of other signaling pathways, together with the identification of the initiating cell, and the development of genetically engineered mice will hopefully lead to biology-based therapeutic strategie...
Ewing's sarcoma (ES) primarily affects bones and commonly presents in adolescents and young adults. This paper reports a rare case of extra osseous ES of the scapular region in a 9 years old girl. She was treated by a multidisciplinary approach including surgery, chemotherapy and radiotherapy. She was followed up for two years and remained well.
Extraskeletal Ewing’s Sarcoma is a rare soft tissue tumor that is morphologically indistinguishable from the more common Ewing’s sarcoma of the bone. Primitive Ewing’s sarcoma of the breast is exceptionally reported. We present the case of a 26-year-old woman with Ewing sarcoma/PNET diagnosed by molecular biology showing the specific t ranscr ipt of Ewing/ per ipheral pr imi t ive neuroectoderm...
PURPOSE The aim of this study was to evaluate the role of radiotherapy (RT) in the management of Ewing sarcoma family tumors (ESFT). MATERIALS AND METHODS Retrospective analysiswas performed on 91 patientswith localized ESFT treated from 1988 to 2012. Primary tumor size was ≥ 8 cm in 33 patients. Surgery, RT, and combined surgery with RT were applied in 37, 15, and 33 patients, respectively. ...
Supplementary Figure S1: (A) IC50 of proliferation after treatment with Olaparib: 72 hours versus 6 days. (B) Grafic representation of IC50 of ES cell lines after treatment with Olaparib with regard to ES cell lines1q status. (C) Grafic representation of IC50 of ES cell lines with regard to their p53 status.
Ewing's sarcoma (ES) is an uncommon round cell tumor with an aggressive course affecting mainly children and young adults. Only 1% of cases is reported with jaw involvement and have mandibular predilection. Radiographic finding in ES reflect many destructive nature of the lesion, like osteolysis, cortical erosion, periostitis and soft tissue mass. A case of ES of the mandible is reported with s...
Ewing’s sarcoma (ES) is the second most common malignant bone tumor in children and young adults. Most cases are reported in the bone, and extraosseous Ewing’s sarcoma (ESS) is an extremely rare disease. We present a case of 36 year old female with extraosseous Ewing’s sarcoma developing at the soft tissue in the leg. Their diagnosis was radiological and essentially histological. The Treatment ...
Ewing sarcoma-primitive neuroectodermal tumors (ES/PNETs) constitute a family of neoplasms characterized by a continuum of neuroectodermal differentiations. ES/PNET of the uterus is rare. There are 48 cases of ES/PNET of the uterus published in the literature as far as we know. We describe a case of Ewing sarcoma of the uterus occurring in a 17-year-old woman presenting with a two-month history...
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