Francesco Prati1,2*, Giulio Guagliumi3, Gary S. Mintz4, Marco Costa5, Evelyn Regar6,7, Takashi Akasaka8, Peter Barlis9, Guillermo J. Tearney10,11, Ik-Kyung Jang12, Elosia Arbustini13, Hiram G. Bezerra5, Yukio Ozaki14, Nico Bruining6,7, Darius Dudek15, Maria Radu6,7, Andrejs Erglis16, Pascale Motreff17, Fernando Alfonso18, Kostas Toutouzas19, Nieves Gonzalo20, Corrado Tamburino21, Tom Adriaensse...

Three horse-derived antivenoms were tested for their ability to neutralize lethal, hemorrhagic, edema-forming, defibrinating and myotoxic activities induced by the venom of Bothrops atrox from Antioquia and Chocó (Colombia). The following antivenoms were used: a) polyvalent (crotaline) antivenom produced by Instituto Clodomiro Picado (Costa Rica), b) monovalent antibothropic antivenom produced ...

Prey availability affects many aspects of predators' life history and is considered a primary factor influencing individuals' decisions regarding spatial ecology and behavior, but few experimental data are currently available. Snakes may represent ideal model organisms relative to other animal groups for addressing such resource dependency, due to a presumably more direct link between food reso...

Myotoxic phospholipases A₂ (PLA₂) are responsible for many clinical manifestations in envenomation by Bothrops snakes. A new myotoxic acidic Asp49 PLA₂ (BaCol PLA₂) was isolated from Colombian Bothrops asper venom using reverse-phase high performance liquid chromatography (RP-HPLC). BaCol PLA₂ had a molecular mass of 14,180.69 Da (by mass spectrometry) and an isoelectric point of 4.4. The compl...

Myotoxic phospholipases A2 are responsible for many clinical signs in envenomation by Bothrops snakes. A new myotoxic acidic PLA2 Asp 49 was isolated from Colombian Bothrops asper venom. It was isolated by high efficiency liquid chromatography and named BaCol PLA2. It had a molecular weight of 14180.69 Da and an isoelectric point of 4.4. The complete sequence obtained by cDNA cloning, with acce...

This paper provides the first checklists for Nepomorpha (12 spp.), Gerromorpha (10 spp.) and Leptopodomopha (5 spp.) of the Tuscan Archipelago; summarizing and updating the knowledge for this area. The presence of the family Micronec- tidae is recorded for the first time in the Archipelago, as well as six species: Nepomorpha - Micronecta scholtzi (Fieber, 1860), Sigara selecta (Fieber, 1848), S...

Detailed snake venom proteomes for nearly a hundred species in different pitviper genera have accumulated using 'venomics' methodologies. However, venom composition for some lineages remains poorly known. Bothrocophias (toad-headed pitvipers) is a genus restricted to the northwestern portion of South America for which information on venom composition is lacking. Here, we describe the protein co...

BACKGROUND The Hutterites are a religious isolate living in colonies across the North American prairies. This population originated from approximately 90 founders, resulting in a number of genetic diseases that are overrepresented, underrepresented, or unique. The founder effect in this population increases the likelihood that Hutterite couples carry the same recessive mutations. We have design...