نتایج جستجو برای: ethyl cellulose

تعداد نتایج: 63605  

2017
Hadi Afrasiabi Garekani Roshanak Dolatabadi Abbas Akhgari Mohammad Reza Abbaspour Fatemeh Sadeghi

OBJECTIVES This study evaluates the effect of substitution of microcrystalline cellulose (MCC) with ethylcellulose (EC) on mechanical and release characteristics of theophylline pellets. MATERIALS AND METHODS The effect of addition of EC was investigated on characteristics of pellets with varying drug content prepared by extrusion-spheronization. Also the effect of type of granulating liquid ...

Journal: :iranian journal of pharmaceutical research 0
seyed alireza mortazavi department of pharmaceutics, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran. yasaman ghadjahani pharmaceutical sciences branch islamic azad university, tehran, iran hoda mahmoodi pharmaceutical sciences branch islamic azad university, tehran, iran farzaneh mehtarpour pharmaceutical sciences branch islamic azad university, tehran, iran zahra jaffariazar pharmaceutical sciences branch islamic azad university, tehran, iran

the purpose of this study was preparation and evaluation of sustained release matrix type ocular mini-tablets of timolol maleate, as a potential formulation for the treatment of glaucoma. following the initial studies on timolol maleate powder, it was formulated into ocular mini-tablets. the polymers investigated in this study included cellulose derivatives (hec, cmc, ec) and carbopol971p. mann...

2012
Ghada E. Yassin Afaf A. Ramadan

Floating matrix tablets of Glimepiride were developed to enhance its bioavailability by prolonging the gastric residence time in which Glimepiride was chosen as a model drug because of its has incomplete absorption due to its low gastric residence time. Floating matrix tablets were prepared using melt granulation technique. Bees wax was used as a hydrophobic meltable material. Hydroxypropylmeth...

2009
A. V Yadav A. S. Shete

Aceclofenac was formulated as novel enteric microcapsules for improved delivery to the intestine using the polymer ethyl cellulose as the retardant material. Micro encapsulation of aceclofenac was done to achieve a controlled drug release profile suitable for per oral administration. Aceclofenac was used as core and microcapsules were prepared by an emulsion solvent evaporation method. The prep...

2014
Thomas Kellner Heike M. A. Ehmann Simone Schrank Birgit Kunert Andreas Zimmer Eva Roblegg Oliver Werzer

The preparation of thin composite layers has promising advantages in a variety of applications like transdermal, buccal, or sublingual patches. Within this model study the impact of the matrix material on the film forming properties of ibuprofen-matrix composite films is investigated. As matrix materials polystyrene, methyl cellulose, or hydroxyl-ethyl cellulose were used. The film properties w...

Journal: :Chemical & pharmaceutical bulletin 2009
Ashish Babulal Rane Surendra Ganeshlal Gattani Vinayak Dinkar Kadam Avinash Ramrao Tekade

The aim of present investigation was to develop press coated tablet for pulsatile drug delivery of ketoprofen using hydrophilic and hydrophobic polymers. The drug delivery system was designed to deliver the drug at such a time when it could be most needful to patient of rheumatoid arthritis. The press coated tablets containing ketoprofen in the inner core was formulated with an outer shell by d...

The purpose of this study was preparation and evaluation of sustained release matrix type ocular mini-tablets of timolol maleate, as a potential formulation for the treatment of Glaucoma. Following the initial studies on timolol maleate powder, it was formulated into ocular mini-tablets. The polymers investigated in this study included cellulose derivatives (HEC, CMC, EC) and Carbopol971P. Mann...

The purpose of this study was preparation and evaluation of sustained release matrix type ocular mini-tablets of timolol maleate, as a potential formulation for the treatment of Glaucoma. Following the initial studies on timolol maleate powder, it was formulated into ocular mini-tablets. The polymers investigated in this study included cellulose derivatives (HEC, CMC, EC) and Carbopol971P. Mann...

2014
Khalid Akhter Ansari Kunal Pratap Pagar Shoeb Anwar Pradeep Ratilal Vavia

The objective of this research work was to design, develop and optimize the self micro-emulsifying drug delivery system (SMEDDS) of Felodipine (FL) filled in hard gelatine capsule coated with polymer in order to achieve rapid drug release after a desired time lag in the management of hypertension. Microemulsion is composed of a FL, Lauroglycol FCC, Transcutol P and Cremophor EL. The optimum sur...

2014
Belkiz Uyar Oya Nermin Sivrikoz Ugur Ozdemir Teslima Dasbasi Handan Sacar

OBJECTIVES The purpose of this study was to analyze the effects of soybean extracts obtained using different extraction methods on the skin of female rats. METHOD A total of 64 female Sprague-Dawley rats were divided into 8 equal groups. Various extracts were administered to the female rats by oral gavage for one month. The groups comprised carboxymethyl cellulose-free control, carboxymethyl ...

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