The aim of the present study was to determine the chemical structures of the isolated compounds, the essential oil and fatty acid compositions of Mentha longifolia subsp. noeana with their biological activities. Ursolic acid (1), uvaol (2), stigmast-5-ene-3-yl formate (3), stigmast-5-en-3-one (4), -sitosterol (5), bis(2ethylhexyl) benzene-1,2-dicarboxylate (6), hexacosyl (E)-ferulate (7) and ...

We investigated the psychostimulant, rewarding, and anxiolytic-like effects of pulegone. Possible interactions between pulegone and menthol concerning their psychostimulant effect were also analyzed. General mouse activity after pulegone treatment, and the interacitons between pulegone and menthol, were determined in the open field. The anxiolytic-like activity, motor coordination and strength ...

We examined the biotransformation of enantiomeric pairs of enones such as pulegone and carvone in recombinant Escherichia coli expressing Nicotiana tabacum pulegone reductase. It was found that recombinant E. coli cells acquired the ability for stereospecific hydrogenation of the exocyclic C=C double bond of pulegone. However, stereospecificity in hydrogenation with the recombinant E. coli cell...

in several field observation of this research ,the main ecological requirenments and ethnopharmacological data about  the traditional uses  of ziziphora clinopodioides lam. were recorded. the aerial parts of plant were collected in blooming from bovanloo mountain in september 2013 (1728 m ) in north khorasan razavi.  essential oil was obtained by hydro-distillation and  analyzed by gc-ms. metha...

background: mentha longifolia is one of the aromatic medicinal plant belongs to lamiaceae family. there are some active ingredients in the essential oil of m. longifolia, which potentially could impair the hepatic function. the aim of this study was to find the maximum dose of essential oil of m. longifolia (eoml) that does not show any hepatic deterioration. methods: adult wistar rats fed diff...

We evaluated the acute toxicities and the physiological effects of plant monoterpenoids (eugenol, pulegone, citronellal and alpha-terpineol) and neuroactive insecticides (malathion, dieldrin and RH3421) on flight muscle impulses (FMI) and wing beat signals (WBS) of the blow fly (Phaenicia sericata). Topically-applied eugenol, pulegone, citronellal, and alpha-terpineol produced neurotoxic sympto...

Peppermint has considerable commercial value and widely cultivated for essential oil production, especially menthol. The aim of this study was to determine the quantitative expression of pulegone reductase (pr), menthofuran synthase (mfs) and limonene synthase (ls) genes in menthol biosynthesis pathway in Mentha x piperita , using semiquantitative RT-PCR analysis and evaluating menthol producti...

background & aim: different species from mint family (lamiaceae) are used as spices and fragrance in food or as medicine against viral or microbial diseases in many countries for generation. lamiaceae family contains 46 genus and 410 species. one of the valuable and medicinal species of this family is ziziphora clinopodioides lam. this species contains the essential oil with pulegone as maj...

In several field observation of this research ,the main ecological requirenments and ethnopharmacological data about  the traditional uses  of Ziziphora clinopodioides Lam. were recorded. The aerial parts of plant were collected in blooming from Bovanloo mountain in September 2013 (1728 m ) in North Khorasan Razavi.  Essential oil was obtained by hydro-distillation and  analyzed by GC-MS. Metha...