Abstract Achalasia is a primary defect of esophageal motility unknown aetiology, characterised by peristaltic dysfunction the esophagus and impaired relaxation lower sphincter. The most common symptoms are dysphagia, regurgitation, weight loss, chest burning. There various treatment options for achalasia: botulinum toxin injections, pneumatic dilatation, Heller myotomy, peroral endoscopic myoto...

Achalasia is a rare motility disorder of the esophagus which results from lack of enervation of the lower esophageal sphincter muscles and leads to dilatation of proximal esophagus. Patients with achalasia presents typically with dysphagia, vomiting of undigested food and failure to thrive. Cough can be present in achalasia patients due to aspiration of food or due to airway compression by the ...

Achalasia is one of the most studied esophageal motility disorders. However, the pathophysiology and reasons that patients develop achalasia are still unclear. Patients often present with dysphagia to solids and liquids, regurgitation, and varying degrees of weight loss. There is significant latency prior to diagnosis, which can have nutritional implications. The diagnosis is suspected based on...

Achalasia cardia is a neuromuscular disorder of unknown etiology involving the body of the esophagus and lower esophageal sphincter (LES). It is characterized by aperistalsis of the body of the esophagus and failure of relaxation of lower esophageal sphincter. It usually affects patients between the ages of 30 and 60 years. It is unusual in childhood and extremely rare in infants. We report two...

Gastroesophageal reflux disease is a widespread chronic in which stomach or duodenal contents rise up into the esophagus. Esophageal spasm and achalasia cardia are poorly studied disorders associated with impaired neuromuscular impulse transmission motor discoordination of esophagus, manifested by chest pain dysphagia. The article presents clinical case young patient gastroesophageal history at...

Esophageal achalasia is a neuromuscular disorder of unknown etiology characterized by abnormal motility and failure of relaxation of lower esophageal sphincter, with its usual presentation in fourth and fifth decades of life. It is an unusual lesion in childhood and extremely rare under the age of one year. We report a 7-month-old child with esophageal achalasia treated with modified Heller's e...

BACKGROUND Association between esophageal achalasia/ gastroesophageal reflux disease (GERD) and cholelithiasis is not clear. Epidemiological data are controversial due to different methodologies applied, the regional differences and the number of patients involved. Results of concomitant cholecistectomy associated to surgical treatment of both diseases regarding safety is poorly understood. A...

Achalasia is the best understood and most readily treatable esophageal motility disorder. It serves as a prototype for disorders of the enteric nervous system with degeneration of the myenteric neurons that innervate the lower esophageal sphincter (LES) and esophageal body. Investigations into the pathogenesis have highlighted the importance of nitric oxide and the possible role of an autoimmun...

Various operative techniques have been used for esophageal achalasia, but a definitive technique has not been established yet. During 1958-1994, 117 patients with esophageal achalasia were treated at our clinic. The techniques of Heller and Wendel or the modified Girard method have been successfully performed on 83 cases without any postoperative accidents. In 72 (87%) of these cases, the opera...

Achalasia cardia is a motility disorder of the esophagus characterized by failure of relaxation of the lower esophageal sphincter. Nitrates and calcium channel blockers, pneumatic dilatation, botulinum toxin injection and surgical myotomy have been described in literature as possible management options. We present a patient who presented with achalasia and was co-incidentally diagnosed to have ...