To truly understand the equine gastrointestinal tract, one has to accept the fact that very likely it was designed by a committee. Most equine practitioners who have dealt with horses with colic accept this fact without hesitation. As a result, the aspiring equine practitioner has to face several rather daunting tasks, namely 1) making sense of the anatomy of the horse’s gastrointestinal tract,...

BUCHHEIT, TERESA MARIE. Effects of the Prostaglandin Analogue Misoprostol on TNFAlpha Release by Activated Equine Leukocytes. (Under the direction of Dr. Samuel Jones). The magnitude of LPS-induced equine health problems cannot be over-estimated since endotoxemia is intimately involved in the pathogenesis of gastrointestinal disorders that cause colic, the leading cause of death in adult horses...

Aquaporins (AQPs) play fundamental roles in water and osmolyte homeostasis by facilitating water and small solute movement across plasma membranes of epithelial, endothelial, and other tissues. AQP proteins are abundantly expressed in the mammalian kidney, where they have been shown to play essential roles in fluid balance and urine concentration. Thus far, the majority of studies on renal AQPs...

1. State of the Art in 1963 It was in 1963 that I received my DVM from Cornell University. Developing a specialty in equine gastroenterology was the furthest thing from my mind. I was planning to be a cow doctor. Perhaps it was because of that bias, or because my memory is failing, that I remember virtually nothing that we might have been taught about equine gastrointestinal (GI) problems, exce...

ABST RACT Assessment of pain is vital for colic treatment. The purpose of this study was to revalidate a refined version of the behaviour-based Equine Acute Abdominal Pain Scale (EAAPS). Based on an earlier study, behaviours in the scale were removed or replaced. Ten behaviours remained. For revalidation, forty films of horses with colic were presented by computer-generated random order to two ...