Sheep pox and enterotoxemia are important diseases of sheep, and these diseases cause severe economic losses to sheep farmers. The present study was undertaken to evaluate the potential of formaldehyde-inactivated recombinant epsilon toxin as a vaccine candidate. The potency of the recombinant epsilon toxoid with aluminum hydroxide as an adjuvant in sheep was determined. Vaccinated sheep were p...

Diphtheria Toxin Repressor (dtxR) Gene-Based Genetic Diversity of Corynebacterium diphtheriae Isolated in Jakarta, Indonesia, 2018–2019

Members of the human beta-globin gene family are expressed at discrete stages of development and therefore provide an important model system for examining mechanisms of temporal gene regulation. We have previously shown that expression of the embryonic beta-like globin gene (epsilon) is mediated by a complex array of positive and negative upstream control elements. Correct developmental stage- ...

Ethanol and other drugs of abuse increase synaptic dopamine levels; however, little is known about how ethanol alters dopaminergic signaling. We have reported that ethanol induces translocation of delta and epsilon protein kinase C (PKC) in neural cells in culture. Using NG108-15 and Chinese hamster ovary cell lines that express the dopamine D2 receptor (D2R), we show here that the D2R agonist ...

small polygroups are multi-valued systems that satisfy group-likeaxioms. using the notion of “belonging ($epsilon$)” and “quasi-coincidence (q)” offuzzy points with fuzzy sets, the concept of ($epsilon$, $epsilon$ $vee$ q)-fuzzy subpolygroups isintroduced. the study of ($epsilon$, $epsilon$ $vee$ q)-fuzzy normal subpolygroups of a polygroupare dealt with. characterization and some of the fundam...

We have isolated Clostridium perfringens type B, an epsilon toxin-secreting bacillus, from a young woman at clinical presentation of Multiple Sclerosis (MS) with actively enhancing lesions on brain MRI. This finding represents the first time that C. perfringens type B has been detected in a human. Epsilon toxin's tropism for the blood-brain barrier (BBB) and binding to oligodendrocytes/myelin m...

The aim of this study was to determine the presence of genes coding for alpha (cpalpha), beta (cpbeta), epsilon (epsilontx), iota (iotaA), enterotoxin (cpepsilon) and beta2 (cpbeta2) toxins in Clostridium perfringens isolates from broiler chickens and parent broiler breeder hens, using multiplex polymerase chain reaction (PCR) assay. The prevalence of C. perfringens in the intestinal segments a...

small Polygroups are multi-valued systems that satisfy group-likeaxioms. Using the notion of “belonging ($epsilon$)” and “quasi-coincidence (q)” offuzzy points with fuzzy sets, the concept of ($epsilon$, $epsilon$ $vee$ q)-fuzzy subpolygroups isintroduced. The study of ($epsilon$, $epsilon$ $vee$ q)-fuzzy normal subpolygroups of a polygroupare dealt with. Characterization and some of the fundam...